Optimizing Resuscitation After Cardiac Arrest in the Community

• Conditions: Cardiopulmonary Arrest Outcome

• Registration Number: NCT00998140
• Lead Sponsor: Shaare Zedek Medical Center

Brief Summary

Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs.

Study hypotheses:

1. Subpopulations for whom intervention is futile/counter-productive are identifiable

2. Substantial waste of resources can be avoided

3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

Detailed Description

Not available

Study Timeline

• Study Start: 2009-03
• Study First Submitted: 2009-10-18
• Study First Submitted QC: 2009-10-19
• Study First Posted: 2009-10-20
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-13
• Last Update Posted: 2020-11-16
• Primary Completion: 2021-10
• Study Completion: 2021-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1600

Inclusion Criteria

• All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Exclusion Criteria

• Patients with do-not-resuscitate orders or an advance directive to that effect.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Shaare Zedek Medical Center; 🇮🇱 Jerusalem, Israel