Multislice computed tomography coronary angiography in patients with stable and unstable angina: a multicenter study.
Completed
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 320
Inclusion Criteria
Symptomatic patients with stable angina (N=160) and unstable angina (N=160) who are scheduled for diagnostic invasive coronary angiography will be enrolled into the study.
In addition these patients also need to fulfill the following inclusion criteria.
a) male and female younger than 70 years,
b) stable angina pectoris that warrants further evaluation by coronary angiography and revascularization by percutaneous coronary intervention,
c) stable heart rhythm,
d) heart rate less than 70 b.p.m. (either spontaneous or drug-induced) and
Exclusion Criteria
Patients will be excluded if they are:
1. Older than 70 years; and
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diagnostic accuracy in terms of sensitivity, specificity and predictive value of MS-CT to detect significant obstructive coronary lesions (>50% lumenal diameter reduction with QCA) using the diagnostic invasive coronary angiogram as the reference standard. <br />The costs, effectiveness, and the cost-effectiveness of non-invasive MS-CT coronary angiography as an initial test will be compared to diagnostic invasive coronary angiography.
- Secondary Outcome Measures
Name Time Method