Study of VZV-specific immune response induced by intradermal injection of Varicella vaccine
Not Applicable
- Conditions
- healthy adult
- Registration Number
- JPRN-UMIN000020913
- Lead Sponsor
- ara Medical University
- Brief Summary
Intradermal injection with one-fifth dose VZV vaccine showed a similar or greater effect on VZV-specific cellular immunostimulation than conventional subcutaneous injection.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
Not provided
Exclusion Criteria
excluding criteria: patients with acute conditions; patients with underlying diseases, malignant disease, autoimmune diseases, and renal failure with serum creatinine greater than 2; smoker; treated with steroid, immunosuppressant drugs or antiplatelet drugs; with allergic reaction against varicella vaccine or pneumococcal vaccine; dermatological disorder unable to judge if skin test reaction or not; herpes zoster patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method enhancement of CMI VZV-skin test reaction 6W,1Y,2Y 3Y after injection
- Secondary Outcome Measures
Name Time Method antibody titer safety