跳至主要内容
临床试验/NCT06443385
NCT06443385已完成不适用

E-mails to Nudge Safer and Better-Informed Prescribing of Risky Drugs

Columbia University1 个研究点 分布在 1 个国家目标入组 7,872 人开始时间: 2024年7月17日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
7,872
试验地点
1
主要终点
Rate of PDMP Engagement

研究概览

简要总结

This study will test e-mails to encourage engagement with the Minnesota prescription monitoring program (PMP/PDMP) and will evaluate the effect of these e-mails on PMP/PDMP use and controlled substance prescribing.

详细描述

Drug overdose deaths have skyrocketed in recent years, and many overdoses continue to involve prescribed medications like opioids and stimulants. At the same time, state prescription drug monitoring programs (PDMPs), which help clinicians prescribe these medications safely, remain underused. In Minnesota, 32% of opioid prescriptions are written by clinicians who do not use the PDMP. In many states, including Minnesota, policymakers have limited tools to raise PDMP use even though it is often required under state law. To address this policy dilemma, this study will test e-mails designed to facilitate PDMP use and evaluate their effects on PDMP use and controlled substance prescribing. This study will include a projected 7,126 physician and physician assistant prescribers of opioids and other controlled substances who lack active PDMP accounts, never query the PDMP, or query the PDMP infrequently relative to their prescribing volume. To generate evidence on clinician motivation for responding to encouragement, the study will randomly vary messaging to focus on legal requirements to use the PDMP vs. clinical benefits of the PDMP.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Minnesota physician or physician assistant
  • Controlled substance prescriber not following state requirements to maintain an active PDMP account, or opioid prescriber not searching the PDMP or infrequently searching the PDMP

排除标准

  • No e-mail address available

研究组 & 干预措施

Legal Mandate Messaging

Experimental

干预措施: PDMP Legal Mandate E-mail (Behavioral)

Clinical Benefit Messaging

Experimental

干预措施: PDMP Clinical Benefit E-mail (Behavioral)

Control

No Intervention

结局指标

主要结局

Rate of PDMP Engagement

时间窗: 2 months

An indicator for increased PDMP engagement during the 2-month period after the first e-mails were sent. It will indicate whether the level of engagement rose from the baseline level that resulted in the clinician's enrollment into the study. For clinicians who lacked an account, the outcome will indicate whether they created one; for clinicians with an inactive account, the outcome will indicate whether they reactivated it. For those who never searched, it will indicate any search, and for those who rarely searched, it will indicate whether their search rate rose.

Volume of Potentially Guideline-discordant Opioid Prescribing

时间窗: 2 months

A composite of several measures of potentially guideline-discordant opioid prescribing. These will include: 1. Opioid co-prescriptions with other opioids 2. Opioid co-prescriptions with benzodiazepines 3. Opioid co-prescriptions with gabapentinoids 4. High daily opioid doses 5. Long-duration opioid prescriptions to opioid-naïve individuals

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Adam Sacarny, PhD

Associate Professor of Health Policy and Management

Columbia University

研究点 (1)

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