Upper Gastrointestinal Lesions in Crohn's Disease: a Cross-sectional Cohort Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- the incidence of different upper gastrointestinal lesions
研究概览
简要总结
A cross-sectional study was performed from 2017 to 2018. Consecutive Crohn's disease patients diagnosed in the Inflammatory bowel disease center of the Sixth Affiliated Hospital of Sun Yat-sen University were recruited. All patients underwent upper gastrointestinal endoscopy and biopsy by two defined endoscopists and two pathologists, the basic information were collected at the same time, in order to assess the prevalence of upper gastrointestinal involvement, and determine the role of upper gastrointestinal endoscopy in adult Crohn's disease patients, irrespective of upper gastrointestinal symptoms.
研究设计
- 研究类型
- Interventional
- 干预模型
- Sequential
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age is 18 years old or older
- •patients with diagnosis of Crohn's disease
排除标准
- •diagnostic data were incomplete
- •patients with malignant tumor
- •use of PPIs or non-steroidal anti-inflammatory drugs in the preceding 4 weeks
研究组 & 干预措施
adult patients with Crohn's disease
All adult patients(18 years old or older) with Crohn's disease underwent gastroscopy; patients with diagnosed and treated Crohn's disease had gastroscopy performed during the re-examination, and patients diagnosed with Crohn's disease for the first time had gastroscopy performed during the initial consultation.
干预措施: gastroscopy (Other)
结局指标
主要结局
the incidence of different upper gastrointestinal lesions
时间窗: 1 year
The incidence of different characteristic lesions of upper gastrointestinal in CD patients.
次要结局
未报告次要终点
研究者
Xiang Gao
Clinical Professor
Sixth Affiliated Hospital, Sun Yat-sen University