Untersuchung Intraoperativ Entnommener Subkutaner Fettgewebeproben Früh- Und Reifgeborener Auf Die Fettsäure-Zusammensetzung Der Triglyceride Und Der Phospholipide Mit Speziellem Fokus Auf Die Mehrfach ungesättigten Fettsäuren Docosahexaensäure Und Arachidonsäure Wissenschaftliche Untersuchung Bei Minderjährigen
试验速览
- 阶段
- 不适用
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Fatty acid composition of the subcutaneous adipose tissue and plasma
研究概览
简要总结
The fatty acid composition in blood and subcutaneous adipose tissue of infants that have an clinical indicated operation is studied.
详细描述
Collection of:
- subcutaneous adipose tissue of term infants and preterms after birth and at term during a clinically indicated operation.
- blood before the operation.
Measurement of the fatty acid composition (especially arachidonic acid and docosahexaenoic acid) in subcutaneous adipose tissue and blood.
Aim is to compare the composition of the fatty acids in blood and adipose tissue of preterms at term and term infants. To calculate the fatty acid value in each infant the proportion of adipose tissue is determined with PEAPOD before discharge from hospital.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 6 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •meeting criteria of the 3 cohorts
排除标准
- •metabolic diseases of the infant
- •genetic diseases
- •missing agreement for the study
结局指标
主要结局
Fatty acid composition of the subcutaneous adipose tissue and plasma
时间窗: at the time of the operation
Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms at term compared to the composition of infants after birth (within 14 days).
次要结局
- Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms with abdominal problems(time of the first operation until discharge home (at a postnatal age of up to 4-5 months at the most in very preterm infants))
- Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms with abdominal problems and preterms without abdominal problems at term(time of the first operation until discharge home (at a postnatal age of up to 4-5 months at the most in very preterm infants))