Effects of low-level and high-intensity laser therapy as an adjunct to rehabilitation exercise in the management of adults with mild to moderate knee osteoarthritis.

Not Applicable

Completed

• Conditions: knee osteoarthritis; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12621001694808
• Lead Sponsor: BTL Industries Malaysia Sdn Bhd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-12-10
• Study Completion: 2022-10-31
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

The inclusion criteria will be: (1) adults of both genders aged 18 to 75 years, (2) diagnosed with symptomatic (pain and/or stiffness) unilateral or bilateral knee osteoarthritis based on the American College of Rheumatology criteria (Nazari et al., 2019), (3) persistent knee pain with intensity at least 3 on a 10-cm visual analog scale (VAS) for more than 3 months during activities such as going up-and downstairs, sitting or squatting (Alayat et al., 2017, Nazari et al., 2019), (4) degenerative osteoarthritic knee of grade 2 (mild) to 3 (moderate) or less according to the Kellgren-Lawrence classification; verified by knee radiograph performed during the last 6 months (Kheshie et al., 2014).

For bilateral knee osteoarthritis, the most painful knee based on pain score will be taken for evaluation; whereas, if findings were identical, the dominant side of the knee would be included (Yurtkuran et al., 2007, Kheshie et al., 2014)

Exclusion Criteria

The exclusion criteria will be as follows: (1) severe knee osteoarthritis (grade 4) according to the Kellgren-Lawrence classification, (2) other pathological conditions such as rheumatic disease, previous hip or knee joint replacement, congenital dysplasia, osteochondritis dissecans, intra-articular fractures, septic arthritis, Perthes disease, ligament or meniscus injury and plica syndrome, (3) history of acute traumatic injuries to the knee or lower extremities (Nazari et al., 2019), (4) patients who had received intra-articular injections (e.g., corticosteroid, hyaluronic acid, or blood-derived products) for knee osteoarthritis during the last 6 months (Kheshie et al., 2014, Alayat et al., 2017, Nazari et al., 2019), (5) uncontrolled medical conditions (e.g., heart, blood, or respiratory disease) that would limit participation with the assessments and intervention program (Alayat et al., 2017), and (6) current participation in another knee osteoarthritis-related interventional study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified