A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer
Not Applicable
Completed
- Conditions
- Esophageal Neoplasms
- Interventions
- Device: OlympusDevice: Cellvizio
- Registration Number
- NCT02182804
- Lead Sponsor
- King Chulalongkorn Memorial Hospital
- Brief Summary
This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
- Age over 20 years
- Having histological-confirmed diagnosis of head and neck cancer
- Having no esophageal symptoms
Exclusion Criteria
- Having index cancer of nasopharynx
- History of esophageal surgery
- Having esophageal stricture or obstruction
- Having esophageal varices
- Known case of esophageal cancer
- Uncorrectable coagulopathy and thrombocytopenia
- Pregnancy
- Thyrotoxicosis
- Creatinine clearance less than 30 ml/min
- Allergy to iodine or fluorescein.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Study Olympus probe-based confocal laser endomicroscopy narrow band imaging with magnification Study Cellvizio probe-based confocal laser endomicroscopy narrow band imaging with magnification
- Primary Outcome Measures
Name Time Method Accuracy an expected average of 2 weeks Diagnostic performance of the pCLE and M-NBI in Lugol's voiding lesions size larger than 5 millimeters.
- Secondary Outcome Measures
Name Time Method