A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer

Not Applicable

Completed

• Conditions: Esophageal Neoplasms

• Registration Number: NCT02182804
• Lead Sponsor: King Chulalongkorn Memorial Hospital

Brief Summary

This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Study First Submitted: 2014-07-01
• Study First Submitted QC: 2014-07-07
• Study First Posted: 2014-07-08
• Status Verified: 2020-08
• Results First Submitted: 2020-08-13
• Results First Submitted QC: 2020-08-13
• Last Update Submitted: 2020-08-13
• Results First Posted: 2020-08-28
• Last Update Posted: 2020-08-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Age over 20 years
• Having histological-confirmed diagnosis of head and neck cancer
• Having no esophageal symptoms

Exclusion Criteria

• Having index cancer of nasopharynx
• History of esophageal surgery
• Having esophageal stricture or obstruction
• Having esophageal varices
• Known case of esophageal cancer
• Uncorrectable coagulopathy and thrombocytopenia
• Pregnancy
• Thyrotoxicosis
• Creatinine clearance less than 30 ml/min
• Allergy to iodine or fluorescein.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Accuracy	an expected average of 2 weeks	Diagnostic performance of the pCLE and M-NBI in Lugol's voiding lesions size larger than 5 millimeters.