NCT02182804已完成不适用
Diagnostic Values of Probe-based Confocal Laser Endomicroscopy (pCLE) and Magnifying Narrow Band Imaging (M-NBI) for Early Neoplasms Detection in Esophageal Lugol'S-voiding Lesions.
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 44
- 主要终点
- Accuracy
研究概览
简要总结
This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 20 years
- •Having histological-confirmed diagnosis of head and neck cancer
- •Having no esophageal symptoms
排除标准
- •Having index cancer of nasopharynx
- •History of esophageal surgery
- •Having esophageal stricture or obstruction
- •Having esophageal varices
- •Known case of esophageal cancer
- •Uncorrectable coagulopathy and thrombocytopenia
- •Pregnancy
- •Thyrotoxicosis
- •Creatinine clearance less than 30 ml/min
- •Allergy to iodine or fluorescein.
研究组 & 干预措施
Study
Experimental
probe-based confocal laser endomicroscopy narrow band imaging with magnification
干预措施: Olympus (Device)
Study
Experimental
probe-based confocal laser endomicroscopy narrow band imaging with magnification
干预措施: Cellvizio (Device)
结局指标
主要结局
Accuracy
时间窗: an expected average of 2 weeks
Diagnostic performance of the pCLE and M-NBI in Lugol's voiding lesions size larger than 5 millimeters.
次要结局
未报告次要终点
研究者
Rapat Pittayanon
Gastroenterologist
King Chulalongkorn Memorial Hospital
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