Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery

Not Applicable

Completed

• Conditions: Rhinosinusitis
• Interventions: Procedure: functional endoscopic sinus surgery; Drug: Dexmedetomidine

• Registration Number: NCT06866145
• Lead Sponsor: Menoufia University

Brief Summary

Dexmedetomidine Infusion in either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery

Detailed Description

the study was prospective randomized single blinded study

Study Timeline

• Status Verified: 2024-03
• Study Start: 2024-05-01
• Study First Submitted: 2025-03-04
• Study First Submitted QC: 2025-03-04
• Study First Posted: 2025-03-10
• Primary Completion: 2025-07-01
• Study Completion: 2025-07-01
• Last Update Submitted: 2025-09-02
• Last Update Posted: 2025-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• American Society of Anesthesiologists (ASA) class I and II patients undergoing endoscopic sinus surgery in the age group from 18-50 years.

Exclusion Criteria

• History of allergy to medications used in the study, refusal of patients to participate, hepatic or renal dysfunction, chronic pain condition, psychological and neurological disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
TIVA group	functional endoscopic sinus surgery	patients receives total intravenous anesthesia
TIVA group	Dexmedetomidine	patients receives total intravenous anesthesia
inhalational group	functional endoscopic sinus surgery	patients receives inhalational anesthesia
inhalational group	Dexmedetomidine	patients receives inhalational anesthesia

Primary Outcome Measures

Name	Time	Method
Surgical field visibility	intraoperative	Surgical field visibility assessed every 15 minutes based on Boezaart scale from 0 to 5 as 0 is the worst score and 5 is the best

Trial Locations

Locations (1)

Menoufia university hospital; 🇪🇬 Shibin Elkom, Egypt

Menoufia university hospital

🇪🇬Shibin Elkom, Egypt