Evaluation of bone metabolism in patients with ankylosing spondylitis
Recruiting
- Conditions
- ankylosing spondylitis10023213
- Registration Number
- NL-OMON33084
- Lead Sponsor
- Medisch Centrum Leeuwarden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
Patients have to fulfil the modified New York criteria for AS or bilateral sacroiliitis with bone marrow oedema on MRI.
Patients have to be 18 years of age or older.
Exclusion Criteria
No informed consent.
Legal incapacity.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Bone regulating and bone turnover markers, bone mineral density, disease<br /><br>activity, physical function, quality of life, inflammation of the entheses and<br /><br>inflammation of the peripheral joints.<br /><br>HLA-B27 and in the future possibly other AS-related genetic factors.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable.</p><br>