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Efficacy of Mindfulness Based Cognitive Therapy for patients with Obsessive Compulsive Disorder

Phase 2
Recruiting
Conditions
F42
Obsessive-compulsive disorder
Registration Number
DRKS00004525
Lead Sponsor
niversitätsklinik für Psychiatrie und PsychosomatikAbteilung Psychiatrie und Psychotherapie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
128
Inclusion Criteria

written informed consent
age 18-70
primary diagnosis of OCD (ICD-10 F42.-)
at least 20 sessions of CBT with ERP within 3 years prior to study
inclusion
clinically relevant OCD, i.e. Y-BOCS global score > 12 at study
inclusion
fulfilled DSM-IV criteria for OCD for a period of = three years prior to
study inclusion, either without an aymptomatic period or an
asymptomatic period of < 6 months

Exclusion Criteria

begun or altered medication within 12 weeks before study inclusion
receiving benzodiazepines
mania (ICD-10 F30.-)
suicidal tendency
current severe depressive episode (BDI>28)
borderline disorder (ICD-10 F60.3)
current substance abuse or substance dependence (ICD-10 F1x.2)
intelligence quotient < 70
psychosis (ICD-10 F20-F29)
severe neurological disorder
indication of Asperger syndrome (ICD-10 F84.5)

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
the severity of obsessive compulsive symptoms as measured by the Yale Brown Obsessive Compulsive Scale, an established and very commonly used semi-structured interview. Assesment time points are pre, post and 6- and 12-months-follow-ups
Secondary Outcome Measures
NameTimeMethod
- depression (Beck Depression Inventory)<br>- global level of psychopathology (Brief Symptom Inventory)<br>- quality of life (World Health Organization Quality of Life abbreviated)<br>- mindfulness (Kentucky Inventory of Mindfulness Skills)<br>- metacognitions (Obsessive Belief Questionnaire, Metacognitions Questionnaire)<br>- psychological flexibility/experiential avoidance (Acceptance and Action Questionnaire)<br>Assesment time points are pre, post and 6- and 12-months-follow-ups<br>
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