Correlation of biomarkers with 28-day mortality in patients with sepsis or septic shock
- Conditions
- Health Condition 1: A488- Other specified bacterial diseases
- Registration Number
- CTRI/2023/08/056771
- Lead Sponsor
- IPGMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Adult patients (= 18 years) admitted for sepsis or septic shock( according to
Sepsis-3 criteria) within 24 hours after admission in the department of critical care
medicine
(1) Under 18 years of age.
(2) Pregnancy.
(3) Shock of other origin.
(4) Acute coronary syndrome, chronic renal disease, chronic liver disease.
(5) Malignancy.
(6) On immunosuppressive therapy, HIV.
(7) Leucopoenia.
(8) Trauma, burn.
(9) Post surgical patients/ patients requires immediate surgical intervention
(10) Resuscitation status from cardiopulmonary arrest,
(11) Antibacterial therapy in the 5 days prior to enrolment,
(12) Do-not-resuscitate status.
(13) Previous hospital admission within 4 week.
(14) Patient taking any anticoagulant and/or Metformin.
(15) History of coagulopathy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -To identify any correlation between biomarkers of sepsis (within 24 hrs <br/ ><br>after icu admission) and 28-day mortality due to sepsis or septic shock. <br/ ><br>Timepoint: 28 DAYS <br/ ><br>
- Secondary Outcome Measures
Name Time Method To identify any correlation between biomarkers of sepsis (within 24 <br/ ><br>hrs after icu admission) and duration of hospital stay. <br/ ><br>- To identify any correlation between biomarkers of sepsis(within 24 <br/ ><br>hrs after icu admission) and degree of organ involvement. <br/ ><br>- To identify early predictor of sepsis related mortalityTimepoint: 28 DAYS