Continuous Infraclavicular Nerve Blocks: Needle Versus Catheter Local Anesthetic Bolus
Trial Snapshot
- Phase
- Phase 4
- Status
- Withdrawn
- Locations
- 1
- Primary Endpoint
- Sensory Level
Study Overview
Brief Summary
The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset sensory block than injecting the initial bolus via the perineural catheter. The study results will help define the optimal local anesthetic bolus introduction technique-needle versus catheter-for peripheral nerve blocks when placing a perineural catheter.
Detailed Description
Specific Aim: The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset sensory block than injecting the initial bolus via the perineural catheter. The study results will help define the optimal local anesthetic bolus introduction technique-needle versus catheter-for peripheral nerve blocks when placing a perineural catheter.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •age ≥ 18 years
- •willing to have bilateral infraclavicular blocks/catheters placed
Exclusion Criteria
- •current daily analgesic use
- •opioid use within the previous 4 weeks
- •any neuro-muscular deficit of either upper extremity
- •body mass index > 30 kg/m2
- •weight < 50 kg [100 lbs]
- •pregnancy
- •incarceration
Arms & Interventions
Local Anesthetic Via Catheter
30mL of Lidocaine (local Anesthetic) will be injected via a perineural catheter at hour 0.
Intervention: Local Anesthetic given via perineural catheter for infraclavicular nerve block. (Procedure)
Local Anesthetic Via Needle
30mL of Lidocaine (local Anesthetic) will be injected via a needle at hour 0.
Intervention: Local Anesthetic given via needle for infraclavicular nerve block (Procedure)
Outcomes
Primary Outcomes
Sensory Level
Time Frame: 120 minutes
EKG pads will be positioned in the 5 major nerve distributions distal to the elbow, ensuring placement is equivalent bilaterally. The primary endpoint will be the time, in minutes, until all 5 nerve territories record \> 60 mA, or 120 minutes-whichever occurs first-since 60 mA is estimated to be equivalent to a surgical incision.
Secondary Outcomes
- Grip Strength(120 Minutes)
- Sensory level for individual nerves(120 Minutes)
Investigators
Brian M. Ilfeld, MD, MS
Associate Professor, In Residence
University of California, San Diego