Comparison of effectiveness and side effects of Mitomycin c and 5 Fluorouracil eye drops used for treating patients with surface tumor of the conjunctiva of the human eye.
Phase 4
- Conditions
- Health Condition 1: C690- Malignant neoplasm of conjunctiva
- Registration Number
- CTRI/2024/04/066329
- Lead Sponsor
- Dr Shroff Charity Eye Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients above 18 years of age diagnosed with ocular surface squamous neoplasia without scleral or orbital invasion with no history of prior treatment for presenting lesion
Exclusion Criteria
1)patients with previous history of receiving treatment for presenting lesion
2)patients with advanced cases of ocular surface squamous neoplasia with scleral or orbital invasion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)% reduction in tumor dimensions(in terms of maximum vertical , horizontal dimensions and thickness) at 2 months and 3 months of starting therapy <br/ ><br>Timepoint: 1)% reduction in tumor dimensions(in terms of maximum vertical , horizontal dimensions and thickness) at 2 months and 3 months of starting therapy <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1)time taken to complete clinical resolution of tumor <br/ ><br>2)side effects/toxicity profile of each drug at the end of the studyTimepoint: 1) time taken for complete clinical resolution is variable <br/ ><br>2)side effect profile at end of study i.e. 1 year 6 months from start