DRKS00030073招募中不适用
Hi-SMILE: Prospective study on stereotactic minimally-invasive laser interstitial thermal therapy in patients with recurrent glioblastoma and high-grade glioma - Hi-SMILE
eurochirurgische KlinikSektion stereotaktische NeurochirurgieUniversitätsklinikum Heidelberg0 个研究点目标入组 30 人开始时间: 2022年8月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Patients of legal age with previously histologically confirmed glioblastoma or high-grade glioma (CNS WHO 4°) and
- •imaging suspicion of supratentorial recurrence
- •- Indication for LITT treatment with biopsy sampling if open resection is considered too risky
- •resection is deemed too risky or not possible by specialist neurosurgeon.
- •(Common factors in favor of LITT treatment:
- •a) tumor volume <30cm3 and/or <3cm diameter along the
- •longest axis of extension
- •b) Karnofsky Performance Index of 70% or higher).
排除标准
- •- Patients not able to give consent
- •- MRI imaging not possible
- •- Expected survival <3 months
- •- Presence of absolute contraindications for general anesthesia and/or surgery
- •- Pregnant patients
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