European Study in Patients With Osteoarthritis, Rheumatoid Arthritis, or Ankylosing Spondylitis at Gastrointestinal Risk: A Retrospective, Non-interventional Study of Vimovo™ Prescribing Patterns
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- Physicians' part of questionnaire score covering speciality, practice setting and NSAIDs prescribing preferences
研究概览
简要总结
The most common pain-relievers used by patients with rheumatic disorders are called non-steroidal anti-inflammatory drugs (NSAIDs). These drugs are effective and well documented, but they can cause ulcers and gastrointestinal side effects. Vimovo™ is a tablet containing naproxen (NSAID) and a gastroprotective agent called esomeprazole. Patients with rheumatic disorders, who are at risk for developing gastrointestinal side effects, and where lower doses of naproxen or other NSAID treatment is not considered sufficient, could use this tablet. The regulatory authorities in many European countries have approved the use of Vimovo™, but they would like to understand how various factors influence the doctors' decision to prescribe the tablet and what is characterizing the patients receiving it. The aim of the study is to answer these questions.
详细描述
European study in patients with osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis at gastrointestinal risk: A retrospective, non-interventional study of Vimovo™ prescribing patterns
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of arthritic disorder (osteoarthritis, rheumatoid arthritis or ankylosing spondylitis) Risk for developing gastrointestinal ulcer Already prescribed Vimovo
排除标准
- •Participation in any interventional drug study at the time Vimovo™ was prescribed
- •Patients started on Vimovo during the first 3 months after country-specific launch date
- •Patients started on Vimovo after the study site is initiated (in order to avoid influence on prescribing decision and recruitment)
结局指标
主要结局
Physicians' part of questionnaire score covering speciality, practice setting and NSAIDs prescribing preferences
时间窗: baseline
Patients' part of questionnaire score covering demography, medical history and Vimovo™ prescribing preferences
时间窗: baseline
次要结局
未报告次要终点
