Comparison of effect of 2 methods of giving oxygen: at high flow rate vs traditional oxygen delivery to obese patients after fastrack (surgery with fast recovery) heart surgery with on atelectasis (air sacs of lung do not fill with air) in which the patients will be randomly divided into groups
Not Applicable
Completed
- Conditions
- Health Condition 1: I00-I99- Diseases of the circulatory systemHealth Condition 2: E669- Obesity, unspecified
- Registration Number
- CTRI/2022/05/042678
- Lead Sponsor
- King Georges Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of ASA physical status III and IV with BMI >= 30 kg/m2 scheduled to undergo elective cardiac surgery with fast track extubation will be included in this trial.
Exclusion Criteria
1)Heart failure
2)Vasopressor support
3)Severe Pulmonary Hypertension
4)Preoperative atelectasis
5)Preoperative pulmonary disease including - tuberculosis, pleural effusion, restrictive lung disease, COPD , Asthma
6)Contraindication to HFNO including blocked nasal passage / choanal atresia , Trauma / surgery to nasopharynx
7)Negative consent/refusal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of atelectasis after surgery Timepoint: On the day of surgery (in the immediate postoperative period), One day after surgery <br/ ><br>and Two days after surgery
- Secondary Outcome Measures
Name Time Method 1. Severity of atelectasis <br/ ><br>2. Vitals: Heart rate, Blood Pressure, Respiratory Rate, Oxygen saturation and temperature. <br/ ><br>3. Dyspnea Score using modified Borg score <br/ ><br>4. Pain score using Visual analogue scale <br/ ><br>5. PaO2/PiO2 ratio, PCO2, and PaO2 using arterial blood gas <br/ ><br>6. Shunt fraction <br/ ><br>7. Duration of oxygen requirement <br/ ><br>8. Duration of ICU stay <br/ ><br>9. Re-intubation rateTimepoint: Outcome 1-after extubation, day 1 & 3 of surgery <br/ ><br>Outcomes 2,3 & 4 -every 2 hour for 12 hours then day 1,2 & 3 <br/ ><br>Outcome 5 & 6-after extubation, day 1, day2,day3 <br/ ><br>Outcome 7,8 & 9- in the postoperative period