跳至主要内容
临床试验/NCT07605494
NCT07605494已完成不适用

Biceps to Flexor Digitorum Superficialis Tendon Transfer for Finger Flexion Reconstruction After Pan-brachial Plexus Injury

Siriraj Hospital1 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2014年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
17
试验地点
1

研究概览

简要总结

This study is a prospective single-arm surgical protocol evaluating biceps-to-flexor digitorum superficialis (FDS) tendon transfer using a tensor fascia lata graft for restoration of finger flexion in patients with traumatic pan-brachial plexus injury (pan-BPI). Finger flexion reconstruction in intrinsic-minus hands remains challenging, as conventional flexor digitorum profundus (FDP)-based reconstructions may result in clawing and ineffective grasp. The proposed technique aims to improve metacarpophalangeal and proximal interphalangeal joint flexion to enhance functional grasp. Eligible patients are those with pan-BPI who previously underwent nerve transfer and achieved elbow flexion strength of at least Medical Research Council (MRC) grade 4. Patients with significant joint stiffness, severe forearm soft tissue injury, or insufficient elbow flexion strength are excluded. The procedure consists of staged reconstruction followed by tendon transfer with tensor fascia lata graft interposition. Postoperative management includes 4 weeks of immobilization and progressive rehabilitation. The primary outcome is functional finger flexion, while secondary outcomes include complications and reoperation rates.

详细描述

Traumatic pan-brachial plexus injury (pan-BPI) results in severe upper limb dysfunction, with finger flexion restoration remaining challenging. FDP-based reconstructions often produce clawing and ineffective grasp in intrinsic-minus hands. This study proposes biceps-to-FDS tendon transfer using a tensor fascia lata graft to improve MCP and PIP flexion and enhance grasp. This is a prospective single-arm surgical protocol. Eligible patients include those with pan-BPI who have undergone nerve transfer and achieved elbow flexion at least MRC grade 4. Patients with joint stiffness, severe forearm soft tissue injury, or inadequate elbow strength are excluded. The procedure involves staged reconstruction, followed by tendon transfer with graft interposition. Postoperatively, immobilization is maintained for 4 weeks, with gradual rehabilitation. Primary outcome is functional finger flexion. Secondary outcomes include complications and reoperation.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Brachial plexus injury patients with successful nerve transfer surgery for elbow flexion
  • Elbow flexion motor power at least grade 4

排除标准

  • Stiffness of proximal interphalangeal (PIP) joint
  • Stiffness of metacarpophalangeal (MCP) joint
  • Severe soft tissue injury around the forearm

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Panai Laohaprasitiporn, MD

Assistant Professor

Siriraj Hospital

研究点 (1)

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