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Clinical Trials/NCT03895476
NCT03895476
Completed
Not Applicable

A Randomized Controlled Trial to Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting

University of Alabama at Birmingham1 site in 1 country72 target enrollmentJune 8, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Gingival Recession
Sponsor
University of Alabama at Birmingham
Enrollment
72
Locations
1
Primary Endpoint
Pain Assessment (0=No Pain to 10=Worst)
Status
Completed
Last Updated
last year

Overview

Brief Summary

This randomized clinical comparative study will evaluate the postoperative pain following the FGG graft harvest procedure technique covered by four different methods for coverage of the palatal donor site.

Detailed Description

This study will compare the application of : * hemostatic collagen sponge * collagen sponge sealed with abio-adhesive material * Platelet rich fibrin * physical barrier (stent) on the palatal donor sites with the purpose of which one of these will result in least postoperative pain after epithelialized gingival graft (EGG) harvesting.

Registry
clinicaltrials.gov
Start Date
June 8, 2020
End Date
February 27, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hussein Basma

Principal Investigator

University of Alabama at Birmingham

Eligibility Criteria

Inclusion Criteria

  • English speaking
  • At least 18 years old- 70 years old
  • Must be a patient of the UAB Dental School
  • Able to read and understand informed consent document
  • Patients needing soft tissue graft with teeth that have miller class I or II recession (\>=2mm) on the facial aspects
  • Presence of periodontally healthy teeth at the recipient site.
  • Ability of the participants to maintain good oral hygiene
  • Patient not pregnant or breastfeeding
  • Not taking medications known to cause gingival enlargement

Exclusion Criteria

  • Non-English speaking
  • Less than 18 years old, older than 70 years old
  • Smokers/tobacco users
  • Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
  • Patients that have severe gingival recession (Miller class III and IV) or \< 2 mm.
  • Presence of periodontal disease at the recipient site.
  • Poor oral hygiene
  • Patient pregnant or breastfeeding
  • Taking medications known to cause gingival enlargement

Outcomes

Primary Outcomes

Pain Assessment (0=No Pain to 10=Worst)

Time Frame: day 14

To assess the pain outcomes using the visual analog scale from 0=No pain to 10=worst, excrutiating pain. Assessed daily from days 1 to 14, Day 14 reported.

Bleeding Assessment

Time Frame: day 14

To assessed the bleeding outcomes using the visual analog scale (VAS) from 0=No bruising/bleeding to 10=severe bruising/bleeding. Assessed daily from days 1 to 14, Day 14 reported.

Secondary Outcomes

  • The Need for Painkiller(day 14)
  • Activity Tolerance(day 14)
  • Amount of Swelling(day 14)

Study Sites (1)

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