A Double Blinded Randomized Controlled Study of Topical Anaesthetics Oxybuprocaine Versus Bupivacaine 0.5% in Intravitreal Injections
Overview
- Phase
- Early Phase 1
- Intervention
- bupivacaine 0.5% and oxubuprocaine
- Conditions
- Pain, Acute
- Sponsor
- Research Institute of Ophthalmology, Egypt
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- verbal pain numerical scaling
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
comparing two local anaesthetic agents, Bupivacaine 0.5% versus Oxybuprocaine used topically to provide surface anaesthesia before IVI procedures.
Detailed Description
In preparation zone, we will cannulate the patients, connect them to the pulse oximetry and we will start providing appropriate surface anaesthesia for an adequate period of time before the patient administration of the injection, by applying the anaesthetic agents, 3 times with 5 minutes interval, for 15 minutes and then waitng the injection All patients are informed that they are going to receive topical anaesthetic agent before the IVI. pain is monitored during the injection by using the 11 points verbal numerical pain scaling as zero is for no pain and 10 is for severe unbearable pain.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients between 30 to 70 years
Exclusion Criteria
- •uncooperative patients
Arms & Interventions
bupivacaine 0.5%
Intervention: bupivacaine 0.5% and oxubuprocaine
oxybuprocaine
Intervention: bupivacaine 0.5% and oxubuprocaine
Outcomes
Primary Outcomes
verbal pain numerical scaling
Time Frame: 10 minutes
11 point scale from 0-10 zero measns No pain 10 means severe unbearable pain