Rhomboid Intercostal and Subserratus / Paravertebral Block

Not Applicable

Not yet recruiting

• Conditions: Thoracic; Analgesia; Anesthesia
• Interventions: Procedure: PLACEBO; Procedure: RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK; Procedure: PARAVERTEBRAL BLOCK

• Registration Number: NCT06253741
• Lead Sponsor: Uludag University

Brief Summary

Postoperative pain is a significant concern following video-assisted thoracoscopic surgery (VATS). Pain after thoracic surgery not only causes a strong stress reaction and adverse emotional experience but also affects postoperative rehabilitation. Hence, different analgesia techniques, including local anesthetic infiltration, intercostal nerve block, paravertebral block, and thoracic epidural anesthesia, have been described to attenuate the intensity of acute postoperative painparavertebral block (PVB) and Rhomboid intercostal block with sub-serratus plane block (RISS) are the two types of plane blocks used for postoperative analgesia after video-assisted thoracoscopic surgery (VATS). This prospective randomized controlled trial was performed to analyze the postoperative analgesic effects of ultra- sound-guided PVB and RISS block after video-assisted thoracoscopic surgery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-02
• Study First Submitted: 2024-02-01
• Study First Submitted QC: 2024-02-09
• Last Update Submitted: 2024-02-09
• Study First Posted: 2024-02-12
• Last Update Posted: 2024-02-12
• Study Start: 2024-03-01
• Primary Completion: 2024-07-01
• Study Completion: 2024-08-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Planned for VATS
• American Society of Anesthesiologists (ASA) class I and II
• Patients aged between 18-80

Exclusion Criteria

• Contraindications to local anesthetic allergy or bupivacaine
• Known or suspected coagulopathy
• Injection site infection
• History of thoracic surgery
• Severe neurological or psychiatric disorder
• Severe cardiovascular disease
• Liver failure
• Renal failure (glomerular filtration rate <15 ml/min/1.73 m2)
• Chronic opioid use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PLACEBO	PLACEBO	The group without any peripheral block application will be included
RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK	RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK	After induction of general anesthesia and endotracheal intubation in the operating room, following the positioning of the patient for surgery, rhomboid intercostal block with sub-serratus plane block (RISS) will be routinely performed in our clinic using 0.25% bupivacaine solution at a dose of 0.5 ml/kg under ultrasound guidance.
PARAVERTEBRAL BLOCK	PARAVERTEBRAL BLOCK	After induction of general anesthesia and endotracheal intubation in the operating room, following the positioning of the patient for surgery, ultrasound-guided paravertebral block (PVB) will be routinely performed in our clinic using 0.25% bupivacaine solution at a dose of 0.5 ml/kg.

Primary Outcome Measures

Name	Time	Method
VAS scores	up to 24 hours	The primary outcome of this study was to compare the analgesia of paravertebral block versus rhomboid intercostal and subserratus plane block in VATS surgery.

Secondary Outcome Measures

Name	Time	Method
Side effects	up to 24 hours	Side effects associated with morphine consumption
morphine consumption	up to 24 hours	The secondary outcome measure in this study was 24-hour morphine consumption.
first analgesia requirement	up to 24 hours	Secondary outcome measures included time to first request for morphine

Trial Locations

Locations (1)

Bursa Uludag University; 🇹🇷 Bursa, Turkey