Randomized control clinical trial to evaluate the efficacy of Triphaldi kashaya gandush and Tannic acid, Choline Salicylate gel local Application in the management of pittaj mukhapaka
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- TO study the efficacy of triphaladi kashaya gandusha given in the dose of 40 ml twice a day for 5 days in pittaj mukhapaka.
研究概览
简要总结
Mukhapaka is pittaja nanatmaj & rakta pradoshaja vikara characterized by vedanayukta vrana in the mukha guha. This study has been undertaken because we come across a number of patients of mukhapaka (stomatitis) in day today practice, It’s incidence is increasing due to poor hygienic conditions, hot & dry climate,poor sanitation. Due to changes in life style, individuals are consuming excessive quantity apathya ahar. i.e. mixed type of food, acidic food, spicy food, cold drinks &additions like chewing tobacco, smoking, drinking alcohol etc. which disturb the internal physiology of body. This causative factors aggrevates the doshas may lead to samprapti of Mukhapaka. Samprapti:- Vitiated Pitta Dosha Causes inflammation & ulceration of oral mucosa, associated with smaller reddish yellow papules develop throughout the mouth this causes severe burning pain, altered taste (Bitter taste), difficulty in mastication deglutition Dosha:-Pitta Sadhyasadhyata:- Sadhya
so in this study treatment modality of gandusha is selected. Among these gandusha, vranaropak drugs are used(Triphala,Patha,Mrudwika,Jaati) Topical countries like India has harsh hot as well cold, humid weathers other are more chances of occurance of various mouth diseases. So it’s need of today to find the specific treatment of mouth diseases, such as mukhapaka. so current topic of research has been taken.
Now a day due to the stressful life, unhygienic conditions, irregular dietary habits and Kapha- Vata
prakopaka Aahara-Vihara tridosha vitiation takes place which results in mukhpaka Hence, there is a
need of better treatment for the management of mukhpaka. All ingredients present in this study
are common and easily available. To limit the use and reduce the side effects of conventional
allopathic treatment Triphaladi kashaya gandusha topic was not used previously in research for
treatment of pittaj mukhapaka. So, to see the results of drug this topic has selected for research per dose. Assessment will be made as regard to the efficacy of both medicines&some will be compared in this present study
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Day(s) 至 60.00 Day(s)(—)
- 性别
- All
入选标准
- •Patients having minimum 3 classical signs and symptoms- asyadaha, asyaruja, asyavirasya, asyavrana.
排除标准
- •Patients undergone recent oral surgeries, known case of HIV, Syphilis, fungal infections, Known case of carcinoma of oral cavity.
结局指标
主要结局
TO study the efficacy of triphaladi kashaya gandusha given in the dose of 40 ml twice a day for 5 days in pittaj mukhapaka.
时间窗: 5 days treatment with follow-ups on 3rd and 5th day.
次要结局
- 1.TO Assess the efficacy of triphaladi kashaya gandush for managment of pittaj mukhapaka(2.To assess the efficacy of tannic acid,choline salicylate gel local application in managment of pittaj mukhapaka)
研究者
Dr Trupti kishor lawangare
PDEAs College Of Ayurved and Research centre
