Endoscopic ablation therapy for superficial esophageal squamous cell carcinoma

Phase 2

Recruiting

• Conditions: superficial esophageal squamous cell carcinoma; Esophageal Squamous Cell Carcinoma; D000077277

• Registration Number: JPRN-jRCT1052220106
• Lead Sponsor: Ishihara Ryu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-10-16
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

Histologically diagnosed squamous cell carcinoma or suspicion of squamous cell carcinoma diagnosed by preoperative endoscopy
Flat morphology (0-IIa, 0-IIb or 0-IIc)
Lesions of 2 cm or lesser in diameter
Lesions with submocosal fibrosis or stenosis due to previous treatment including endoscopic resection and chemoradiotherapy
cEP/LPM or cMM/SM1 of invasion depth diagnosed by preoperative endoscopy
Lesion of 2 cm or more apart from other lesions
No metastatic lesions diagnosed by CT examination
Age is 18 or over
No severe organ dysfunction
Performance Status (ECOG) is 0, 1 or 2
Written informed consent are obtained

Exclusion Criteria

Close to another lesion within 2 cm
Lesons considered to be able to be resected by ESD or EMR safely
Severe psychiatric disease
Active infectious disease
Participating in other interventional study
Patients judged inappropriate by investigator or attending doctor

Study & Design

• Study Type: Interventional
• Study Design: Not specified