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Clinical Trials/NCT04378270
NCT04378270
Completed
Not Applicable

Validation of a Novel Foot Offloading Device

Jeffrey A. Gusenoff, MD1 site in 1 country20 target enrollmentAugust 26, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Plantar Fasciitis, Chronic
Sponsor
Jeffrey A. Gusenoff, MD
Enrollment
20
Locations
1
Primary Endpoint
Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the Pittsburgh Foot Survey.
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Pressure offloading is often considered the most crucial aspect in healing after a foot injury. The investigators have devised a novel foot offloading device (PopSole™) which will allow for customization of the area where there is foot pain, as well as allow for customizable arch support and elevation of the metatarsals. This validation study is aimed to assess improvement of pain with use, ease of use, fit and feel, compliance, and durability over a 4 week period. Validated patient reported outcome measures will be used at baseline, 2 weeks and 4 weeks.

Detailed Description

All subjects will receive the PopSole™ offloading device at the screening/baseline visit, be asked to wear it for 4 weeks, and will be asked to return for an in-person evaluation at week 2 and a completion study visit at week 4. Screening includes the following procedures: 1. Performance of a limited physical exam, inclusive of participant's foot exam with a gait and shoe gear evaluation. 2. Medical and surgical history collection 3. Vital signs, medication profile, allergies, height, weight, and BMI calculation. 4. Collection of demographic information 5. 2D Photographs of both feet will be performed Subjects will be asked to complete: 1. Questionnaires * Foot and Ankle Ability Measure questionnaire * Mayo Clinical Scoring System questionnaire * American Orthopaedic Foot and Ankle Society questionnaire * Manchester Foot and Ankle Disability Index * Pittsburgh Foot Survey 2. Diary cards to document for the feet: pain, bruising, redness of the skin, itching, swelling, bleeding, and any concerns/issues not listed, as well as the location, date and day for each noted symptom. 3. Offload Device Distribution. Devices will be provided for both feet to maintain symmetry and gait stability between the two feet. One pair of devices will be given for use in shoe gear, and one pair will be given for use in a slide in the shower. Follow up visit procedures: Week 2 1. Collection of vital signs, medication profile, weight, and BMI calculation 2. Limited physical exam with a foot exam 3. Adverse Event Reporting 4. Collection and distribution of feet diary cards 5. 2D Photographs of both feet 6. Foot Assessment Questionnaires 7. Device survey - questions about the fit and feel of the device Week 4 The same procedures listed for week 2, with the addition of PopSole™ Device removal and final foot diary card collection.

Registry
clinicaltrials.gov
Start Date
August 26, 2020
End Date
October 20, 2021
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Jeffrey A. Gusenoff, MD
Responsible Party
Sponsor Investigator
Principal Investigator

Jeffrey A. Gusenoff, MD

Professor of Plastic Surgery, & Director, Foot Fat Grafting Institute

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • Aged 18 years or older and able to provide informed consent
  • Subjects with foot pain due to forefoot or heel fat pad atrophy or chronic plantar fasciitis as defined by heel pain for greater than 6 months and failed non-surgical therapy
  • Willing and able to comply with follow up examinations

Exclusion Criteria

  • Concurrent injury to the lower extremity that would effect gait
  • Open foot ulcerations, fractures, or diagnosis of osteomyelitis of the feet
  • Surgical foot intervention in the last 6 months
  • Diagnosis of pregnancy or the intent of the participant to become pregnant during participation in this study
  • Any issue that per the physician's determination would render the patient not appropriate to continue participation in the study (compliance, change in physical status, etc.)

Outcomes

Primary Outcomes

Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the Pittsburgh Foot Survey.

Time Frame: Four Weeks

Pain and function questionnaire measure. Scale for pain ranges from "Very severe" to "Had no pain". Scale for pain interference ranges from " Very much" to "not at all". Scale of functionality ranges from "unable to do" to "without any difficulty" in regards to a range of specified activities. Change is reported in mean foot reported pain score Screening/Baseline visit to 4 Week visit. Questions related to pain include items 1-5, total pain score possible is 25; higher scores indicate less pain reported.

Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale.

Time Frame: Four Weeks

This survey assesses pain (40 points possible, comprises pain subtotal), function (50 points possible, comprises function subtotal; which includes activity limitations, maximum walking distance, difficulty with walking surfaces, gait abnormality, sagittal motion, hindfoot motion and ankle/hindfoot stability, and alignment (10 possible points, comprises alignment subtotal). A total score is calculated out of 100, with higher scores indicating greater impairment. There are also calculated subtotals specific to pain, function and alignment. Change in mean foot pain score on AOFAS from Screening/Baseline Visit to 4 Week Visit. Pain scale is 40 total points, with higher scores meaning less pain.

Participant Compliance With Device

Time Frame: Four Weeks

Documentation of the number of participants who did not wear a single device for the full 4 weeks of the participant's study participation.

Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the Manchester Foot and Ankle Index.

Time Frame: Four Weeks

Pain and function questionnaire assessment. Three responses to a variety of pain and specified activities raging from "On most/every day(s)" which is scored as 2 to "none of the time" which is scored as 0. Summation is made on Functional (0-20 with 20 being the lowest functioning), Personal appearance (0-4 with 4 being the worst), pain (0-10 with 10 being the worst), work/leisure (0-100 with 100 being the worst impact on work/leisure). Change in mean foot pain as reported on the Manchester Foot and Ankle Index from Screening/Baseline visit to 4 Week visit. Pain subscale is questions 13-17, range is 0-10 total points, lower scores indicate less pain.

Device Durability

Time Frame: Four weeks.

Documentation of the number of participants who wore a single device for first 4 weeks of the participant's study participation.

Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the Mayo Clinical Scoring System Questionnaire.

Time Frame: Four Weeks

Pain and function questionnaire. Pain scale from 0 (worst) to 50 (no pain). Activity limitations, orthotic requirements, antalgic gait, neuropathy and plantar heel tenderness are all graded 10 (best) to 10 (worst). Overall summation is excellent (90-100), good (80-89), fair (70-79), poor (\<70). Change in mean foot pain score on Mayo Clinical Scoring System Questionnaire from Screening/Baseline Visit to 4 Week Visit. Pain scale is the first question, 50 total points, with higher scores meaning less pain.

Secondary Outcomes

  • Participants' Reported Satisfaction and/or Difficulties With the Device(Four Weeks)

Study Sites (1)

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