The effect of Nigella sativa oil soft capsule on early menopausal symptom and oxidative markers
- Conditions
- menopause.Menopausal and female climacteric states
- Registration Number
- IRCT20110606006709N19
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 72
Bing at the age of 45-60 years old
Not having a menstrual period over the past 12 months
Earning a score between 15-42 in the Green Assessment Hot flashes
Having a normal menopause
Menopause over the past 5 years (less than 5 years from start of menopause)
Having a normal blood pressure (100/60 to 140 / 90)
The use of tobacco and alcohol
The presence of stressors such as the death of relatives of the first class in the last 6 months
The presence of estrogen-dependent diseases
The use of certain dietary regimens And regular blackberry consumption in the individual
Allergic to spices and essential substances
A history of a history of liver disease, depression or hyperthyroidism
The use of hormonal or herbal medicines to treat menopausal symptoms or nervous system medications for the last 3 months during the study
use of hypertension druges
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total and subdomains scores of early menopause symptoms. Timepoint: Before intervention, 4 and 8 weeks after intervention. Method of measurement: Greene scale.;Serum antioxidant levels (TAC). Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Biochemical methods.;Serum oxidative stress index (MDA). Timepoint: Before interventions and 8 weeks after intervention. Method of measurement: Biochemical methods.
- Secondary Outcome Measures
Name Time Method Frequency of hot flashes. Timepoint: Before interventions, 4 and 8 weeks after intervention. Method of measurement: Checklist for daily counts Frequency of hot flashes.