Incidence, Risk Factors Of Low Anterior Resection Syndrome And Validation Of LARS Score Among Egyptian Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- type of surgery
研究概览
简要总结
Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome.
With advances in colorectal surgery, sparing sphincter surgeries are gaining popularity. But symptoms after surgery can affect the quality of life which has psychomotor effects. Low anterior resection syndrome score is a worldwide known questionnaire. Many countries have accredited validation and translation of this questionnaire, but to our knowledge; it is the first time in Egypt.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age more than 18
- •Diagnosed patients with rectal adenocarcinoma and who received low anterior resection with anastomosis creation or after a minimum 6 months interval after stoma reversal.
- •Tumors of the rectum (2-15 cm) from anal verge
排除标准
- •• cognitive dysfunction
- •Having a history of inflammatory bowel disease or any disease with bowel function impairment namely, Crohn's disease, irritable bowel syndrome, ulcerative colitis or others.
- •Age less than 18
- •Metastatic cancer or tumor recurrence
- •Rectal tumors within 2 cm from anal verge( abdominoperineal)
结局指标
主要结局
type of surgery
时间窗: from 2017 to 2022
from records; surgery was open or laparoscopic
site of tumor
时间窗: from 2017 to 2022
tumor site was determined in Cm from anal verge by colonoscopy
site of anastmosis
时间窗: from 2017 to 2022
site of anastmosis after resection was recorded as colo-rectal or colo-anal
type of meso-rectal excision
时间窗: from 2017 to 2022
excision of meso-rectum was recorded if it was partial or complete
age
时间窗: from 2017 to 2022
age of the patients in years was recorded from patient records
sex
时间窗: from 2017 to 2022
sex of patients was recorded from patient records
type of anastmosis
时间窗: from 2017 to 2022
type of anastmosis(hand sewen or stappled) obtained from records
LARS score
时间窗: from 2017 to 2022
obtained by LARS questionnaire filled by the patient during follow up, it was formed of five questions with different scores on answer choices, interpretaion (0-20) means no LARS, (21- 29) means minor LARS, (30-42) means major LARS
medical disease
时间窗: from 2017 to 2022
medical disease like diabetes and hypertension was recorded from patient records
adjuvant therapy
时间窗: from 2017 to 2022
it was recorded from patients records if he\\she had chemo- or radiotherapy post-operatively
neoadjuvant therapy
时间窗: from 2017 to 2022
history of neoadjuvant therapy before surgery was obtained from patients records
次要结局
未报告次要终点
研究者
Reham Zakaria Mohamed Ahmed
Principal Investigator
Zagazig University