Biomarker Development for Postoperative Cognitive Impairment in the Elderly - BioCog

Charite Berlijn0 个研究点目标入组 500 人开始时间: 待定最近更新: 2024年4月23日

试验速览

暂无简介。

•1. Male and female participants aged 65 years or older,
•2. Ability to give informed consent after verbal and written information,
•3. European ancestry (up till grandparents) for homogeneity reasons for the molecular and genetic investigations.
•Patients also need to meet the following criteria:
•4. Undergoing elective surgery,
•5. Planned operation time > 60 minutes.

•1. MMSE score * 23,
•2. Planned intracranial operation,
•3. Any medical (e.g., vision or hearing) or (neuro)psychiatric condition that would make neuropsychological and/or neuroimaging testing impossible,
•4. Claustrophobia or other reasons (e.g., large tattoos) that make the participant unsuitable to undergo MRI investigations,
•5. Homelessness or other circumstances where the patient would not be reachable by phone or postal services during follow-up,
•6. Participation in an intervention study during study participation,
•7. Admission under judicial or official orders,
•8. Life expectancy less than 1 year,
•9. Withdrawal of informed consent to store, use and distribute pseudomized data which will be gathered during the clinical study period.
•Control participants additionally will be excluded if the following criterion applies:
•10. Elective or emergency surgery during the study period.

发起方

Charite Berlijn