Effect of metformin in patients with concurrent asthma and metabolic syndrome
Phase 3
Recruiting
- Conditions
- Condition 1: Asthma. Condition 2: Metabolic Syndrome.
- Registration Number
- IRCT20220305054199N1
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 110
Inclusion Criteria
Patients with concurrent asthma and metabolic syndrome
Exclusion Criteria
Patients with COPD, hypercapnic respiratory failure, bronchiectasis and respiratory system cancers
Patients with diabetes
People at high risk of malnutrition
Patients with renal failure with creatinine clearance less than 30 cc per minute
Heart Failure class 4
Hemoglobinopathy includes thalassemia major and intermedia and sickle cell anemia
severe liver failure
Patient with severe sepsis
Patient with cancer
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Capillary blood glucose concentration and HbA1C. Timepoint: Before meals and two hours after breakfast at the beginning of hospitalization and discharge and one and three months after discharge. Method of measurement: Using Pars Azmoon Kit.;The rate of asthma attacks leads to emergency room visits and hospitalization. Timepoint: At the time of hospitalization and one and three months after hospitalization. Method of measurement: Asthma control test (ACT) and spirometry and clinical history.;The rate of inflammatory markers. Timepoint: At the time of hospitalization and discharge and one and three months after discharge. Method of measurement: Measurement of C-reactive protein (CRP) levels.;HbA1C. Timepoint: At the time of hospitalization and one and three months after hospitalization. Method of measurement: Using Pars Azmoon Kit.
- Secondary Outcome Measures
Name Time Method Body mass index. Timepoint: At the beginning of hospitalization and one and three months after starting metformin. Method of measurement: By a doctor.