Molecular and histopathological examinations of adhesions in patients with posttraumatic syringomyelia

Recruiting

• Conditions: G95.0; G82; Syringomyelia and syringobulbia; Paraplegia and tetraplegia

• Registration Number: DRKS00008584
• Lead Sponsor: BG Trauma Center Murnau

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-08-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

prior spinal cord injury
- development of posttraumatic syringomyelia

Exclusion Criteria

- Syringomyelia related to other causes (Arnold Chiari, postinfectious etc.)
- absent informed consent

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Displaying histopathological hallmarks of syringomyelia (TGF-beta and pathway mediators in histology, CSF and serum)

Secondary Outcome Measures

Name	Time	Method
identification of other molecular risk factor for posttraumatic syringomyelia (in Serum or CSF, or other than TGF-ß).