Effect of curcumin on radiation induced mucositis

Phase 2

Recruiting

• Conditions: Mucositis.; Diseases of the digestive system; K12. 30

• Registration Number: IRCT20190810044500N17
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Patients with mucositis caused by radiotherapy and chemotherapy
Get at least a dose of 50 gray of radiation during the study
At least two parts of the mouth are involved

Exclusion Criteria

Patients with certain diseases
Unwillingness to continue participating in the study
smoking
Serious dental problems, bruising teeth and the presence of sharp fillings
Presence of artificial teeth importing trauma
Severe systemic disease such as uncontrolled diabetes
With the start of radiation therapy, the patient should be treated by a physician other than for the usual treatment for mucositis.
Simultaneous treatment with Target therapy drugs
Infection

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oral wound size. Timepoint: Before the intervention, after completion of the intervention. Method of measurement: Clinical examination.

Secondary Outcome Measures

Name	Time	Method
Pain or burning sensation in the mouth. Timepoint: Before intervention, after intervention. Method of measurement: Clinical examination and patient based on VAS criteria.;Redness. Timepoint: Before intervention, after intervention. Method of measurement: Clinical examination and patient based on VAS criteria.