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Clinical Trials/NCT01754051
NCT01754051
Completed
Not Applicable

VOLCAN: A Volumetric Coiling in Aneurysm Registry of the Penumbra Coil 400TM System

Penumbra Inc.1 site in 1 country100 target enrollmentJanuary 2013

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Intracranial Aneurysms
Sponsor
Penumbra Inc.
Enrollment
100
Locations
1
Primary Endpoint
Time of fluoroscopic exposure
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This study is a prospective, multi-center registry of patients with intracranial aneurysms who are treated by the PC 400 System. Data for each patient are collected up to 12 ± 3 months post-procedure for the study.

Registry
clinicaltrials.gov
Start Date
January 2013
End Date
October 3, 2017
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients older than 18 years
  • Intracranial aneurysms \>2mm, ruptured or unruptured

Exclusion Criteria

  • Fusiform aneurysms
  • Dissecting aneurysms
  • Aneurysms associated with brain AVMs
  • Multiple aneurysms
  • Re-treated aneurysms
  • Patients in whom endovascular embolization therapies other than PC 400 System are used will be excluded from this study. However, adjunctive use of balloon and stent are acceptable.

Outcomes

Primary Outcomes

Time of fluoroscopic exposure

Time Frame: During the procedure

Packing density with the number of coils implanted

Time Frame: During the procedure

Quality of aneurysm occlusion post-operatively and at 12±3 months post-procedure based on the Raymond Scale

Time Frame: At 1 year post-procedure

Procedural device-related serious adverse events at immediate post-procedure

Time Frame: During the procedure

Secondary Outcomes

  • Adverse events occurring during the procedure and in the 30±7 days following the treatment.(During and at 30 days post-procedure)
  • Acute occlusion of the aneurysm sac at immediate post-procedure(At immediate post-procedure)

Study Sites (1)

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