MedPath

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2
Active, not recruiting
Conditions
Ovarian High Grade Serous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Recurrent Fallopian Tube Clear Cell Adenocarcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Undifferentiated Carcinoma
Recurrent Platinum-Resistant Fallopian Tube Carcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Recurrent Fallopian Tube Endometrioid Adenocarcinoma
Recurrent Platinum-Resistant Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Interventions
Drug: Atezolizumab
Procedure: Computed Tomography
Biological: Bevacizumab
Drug: Pegylated Liposomal Doxorubicin Hydrochloride
Other: Quality-of-Life Assessment
Registration Number
NCT02839707
Lead Sponsor
National Cancer Institute (NCI)
Brief Summary

This phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Chemotherapy drugs, such as pegylated liposomal doxorubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Bevacizumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. It is not yet known which combination will work better in treating patients with ovarian, fallopian tube, or primary peritoneal cancer.

Detailed Description

PRIMARY OBJECTIVES:

I. Estimate the probability of a dose limiting toxicity (DLT) following cycle 1 of experimental regimens (pegylated liposomal doxorubicin hydrochloride \[pegylated liposomal doxorubicin\] \[PLD\] and atezolizumab and PLD/bevacizumab and atezolizumab). (Safety lead-in) II. Estimate and compare the hazard of first progression or death (progression free survival \[PFS\]) of each experimental regimen relative to the reference regimen, PLD and bevacizumab. (Phase II study) III. Estimate and compare the hazard of death and the hazard of first progression or death (PFS) of the experimental regimen relative to the reference regimen. (Phase III) (24-FEB-2021)

SECONDARY OBJECTIVES:

I. Estimate and compare the probabilities of response (objective response rate \[ORR\], either partial or complete response) defined by Response Evaluation Criteria in Solid Tumors (RECIST) version (v)1.1 criteria on each study regimen. (Phase II study) (24-FEB-2021) II. Estimate the frequency and severity of adverse events as classified and graded with Common Terminology Criteria for Adverse Events (CTCAE) in those patients who initiate their randomly assigned study treatment. (Phase II study) (03/19/2018) III. Estimate and compare ORR in each treatment group. (Phase III study) IV. Estimate the frequency and severity of adverse events in those patients who initiate their randomly assigned study treatment. (Phase III study) V. Estimate and compare mean patient reported outcome scores (PROs) as measured by National Comprehensive Cancer Network (NCCN)-Functional Assessment of Cancer Therapy (FACT) ovarian symptom index (NFOSI)-18 disease-related symptoms (DRS). (Phase III study) VI. Estimate and compare the treatment groups on the basis of the PROs: treatment side effects (TSE), function/well-being (FWB), fatigue (Functional Assessment of Chronic Illness Therapy \[FACIT\]-fatigue subscale) and abdominal discomfort (FACT/Gynecologic Oncology Group \[GOG\]-abdominal discomfort \[AD\] subscale). (Phase III study) (10/16/2017)

TRANSLATIONAL SCIENCE OBJECTIVES:

I. To determine whether biomarker levels in pre-treatment tissue, and pre- or on-treatment peripheral blood, and stool specimens are associated with ORR, PFS and/or overall survival (OS).

II. Estimate pre-treatment PD-L1 expression on tumor cells measured by quantitative immunohistochemistry (IHC), and determine whether it is associated with the duration of PFS or overall survival. (Integrated Biomarker) III. Analysis of T cell receptor (TCR) repertoires by deep sequencing of peripheral blood samples. (Exploratory Biomarkers \[10/16/2017\]) IV. Tumor "immunogenicity" as determined by the neo-antigen landscape and characterization of the tumor microenvironment using next-generation sequencing, including but not limited to whole exome sequencing and/or RNA sequencing. (Exploratory Biomarkers \[10/16/2017\]) V. Microbiome analysis via stool sampling. (Exploratory Biomarkers \[10/16/2017\]) VI. To determine whether changes in quantitative biomarker parameters after the first 6 and 12 weeks of therapy predict ORR, PFS and/or OS.

OUTLINE: Patients will be randomized to 1 of 3 arms.

ARM I: Patients receive pegylated liposomal doxorubicin hydrochloride intravenously (IV) over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)

ARM II: Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo computed tomography (CT) on study.

ARM III: Patients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.

In all arms, cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months for up to 2 years, and then every 6 months for up to 3 years.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Female
Target Recruitment
443
Inclusion Criteria
  • Patients must have the psychological ability and general health that permits completion of the study requirements and required follow up
  • Administration of study drugs (pegylated liposomal doxorubicin, bevacizumab, atezolizumab) may have an adverse effect on pregnancy and poses a risk to the human fetus, including embryo-lethality; women of child-bearing potential (WOCBP) must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and for 5 months (150 days) after the last dose of study agent; should a woman become pregnant or suspect she is pregnant while she is participating in this study, she should inform her treating physician immediately. (06/29/2017)
  • Submission of tumor tissue is required for all patients; investigators should check with their site pathology department regarding release of biospecimens before approaching patients about participation in the trial
  • High grade ovarian cancer, including high grade serous; clear cell; endometrioid, grade 3; and others (adenocarcinoma, not otherwise specified [NOS]; mixed epithelial carcinoma; undifferentiated carcinoma); NOTE: low grade serous, mucinous and carcinosarcoma histologies are excluded due to their different underlying genomic features and/or clinical behavior; ovarian cancer = ovarian, fallopian tube or primary peritoneal cancer; required data element: submission of pathology report
  • Recurrent, platinum resistant ovarian cancer (defined as progression within < 6 months from completion of platinum based therapy; the date should be calculated from the last administered dose of platinum therapy)
  • 1-2 prior regimens (including primary therapy); hormonal therapies (e.g., tamoxifen, aromatase inhibitors) will not count toward the prior regimen limit; PARP inhibitors given in the maintenance setting post response to platinum-based therapy will not count as a separate regimen from the preceding platinum-based therapy. (30-OCT-2020)
  • Measurable disease (defined by RECIST v1.1) or evaluable disease (defined as solid and/or cystic abnormalities on radiographic imaging that do not meet RECIST 1.1 definitions for target lesions OR ascites and/or pleural effusion that has been pathologically demonstrated to be disease related in the setting of cancer antigen [CA] 125 >= 2 x upper limit of normal [ULN])
  • Age >= 18
  • Performance status 0, 1 or 2
  • Absolute neutrophil count (ANC) >= 1,500/mcl (within 14 days prior to registration)
  • Platelets >= 100,000/mcl (within 14 days prior to registration)
  • Hemoglobin (Hgb) >= 8 g/dl (within 14 days prior to registration)
  • Creatinine =< 1.5 x institutional upper limit of normal (ULN) (within 14 days prior to registration)
  • Urine protein creatinine (UPC) ratio must be < 1.0 (within 14 days prior to registration); if UPC ratio >= 1, collection of 24-hour urine measurement of urine protein is recommended (24-hour urine protein level must be < 1000 mg for patient enrollment); If UPC ratio cannot be calculated because the urine protein is below the lower limit of detection of the assay this will not exclude the patient (10/22/2018) (30-OCT-2020); UPC ratio of spot urine is an estimation of the 24-hour urine protein excretion - a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm
  • Total bilirubin =< 1.5 x ULN (patients with known Gilbert disease who have serum bilirubin level =< 3 x ULN may be enrolled) (within 14 days prior to registration)
  • Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3 x ULN (AST and/or ALT =< 5 x ULN for patients with liver involvement) (within 14 days prior to registration)
  • International normalized ratio (INR) and activated partial thromboplastin time (aPTT) =< 1.5 x ULN (or on stable dose of therapeutic anticoagulation, such as low-molecular-weight heparin, warfarin or rivaroxaban) (10/16/2017)
  • Thyroid-stimulating hormone (TSH) within normal limits (Euthyroid patients on thyroid replacement therapy allowed provided TSH < ULN) (02/20/2019)
  • The patient or legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information
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Exclusion Criteria
  • Patients with prior allogeneic bone marrow transplantation or prior solid organ transplantation

  • Patients who have had systemic anticancer therapy (e.g., chemotherapy, targeted therapy including PARP inhibitors or bevacizumab) within 3 weeks prior to entering the study (30-OCT-2020)

  • Patients who have had hormonal therapy (e.g., tamoxifen, aromatase inhibitor) within 1 week prior to entering the study

  • Patients with prior treatment with anti-programmed cell death (PD)-1, anti- programmed cell death ligand (PD-L)1 or anti-cytotoxic T-lymphocyte-associated protein (CTLA)-4 therapeutic antibody or other similar agents (10/16/2017)

  • Patients with prior treatment with bevacizumab (or any other anti vascular therapy, e.g., cediranib) for platinum resistant recurrence; (Note: prior bevacizumab in initial therapy and/or platinum sensitive recurrent setting is allowed) (10/16/2017)

  • Patients with prior treatment with PLD

  • Prior radiotherapy to the abdomen or pelvis

  • Patients who have not recovered from adverse events to =< grade 1 (other than alopecia) due to agents administered more than 3 weeks earlier (10/16/2017); however, the following therapies are allowed:

    • Hormone replacement therapy or oral contraceptives
    • Herbal therapy > 1 week prior to cycle 1, day 1 (herbal therapy intended as anticancer therapy must be discontinued at least 1 week prior to cycle 1, day 1)
    • Palliative radiotherapy for bone metastases > 2 weeks prior to cycle 1, day 1
  • Treatment with any other investigational agent within 4 weeks prior to cycle 1, day 1

  • Treatment with systemic immunostimulatory agents (including, but not limited to, interferon [IFN]-alpha or interleukin [IL]-2) within 6 weeks prior to cycle 1, day 1

  • Treatment with systemic immunosuppressive medications (including, but not limited to, prednisone, cyclophosphamide, azathioprine, methotrexate, thalidomide, and anti-tumor necrosis factor [anti-TNF] agents) within 2 weeks prior to cycle 1, day 1

    • Patients who have received acute, low dose, systemic immunosuppressant medications (e.g., a one-time dose of dexamethasone for nausea or steroids as computed tomography [CT] scan contrast premedication) may be enrolled
    • The use of inhaled corticosteroids and mineralocorticoids (e.g., fludrocortisone) for patients with orthostatic hypotension or adrenocortical insufficiency is allowed
  • Patients taking bisphosphonate therapy for symptomatic hypercalcemia within the past 28 days; use of bisphosphonate therapy for other reasons (e.g., bone metastasis or osteoporosis) is allowed

  • Patients with known primary central nervous system (CNS) malignancy or symptomatic CNS metastases are excluded, with the following exceptions:

    • Patients with asymptomatic untreated CNS disease may be enrolled, provided all of the following criteria are met:

      • Evaluable or measurable disease outside the CNS
      • No metastases to brain stem, midbrain, pons, medulla, cerebellum, or within 10 mm of the optic apparatus (optic nerves and chiasm)
      • No history of intracranial hemorrhage or spinal cord hemorrhage
      • No ongoing requirement for dexamethasone for CNS disease; patients on a stable dose of anticonvulsants are permitted
      • No neurosurgical resection or brain biopsy within 28 days prior to cycle 1, day 1
    • Patients with asymptomatic treated CNS metastases may be enrolled, provided all the criteria listed above are met as well as the following:

      • Radiographic demonstration of improvement upon the completion of CNS directed therapy and no evidence of interim progression between the completion of CNS directed therapy and the screening radiographic study
      • No stereotactic radiation or whole-brain radiation within 28 days prior to cycle 1, day 1
      • Screening CNS radiographic study >= 4 weeks from completion of radiotherapy and >= 2 weeks from discontinuation of corticosteroids
  • Known hypersensitivity to Chinese hamster ovary cell products or other recombinant human antibodies

  • History of severe allergic, anaphylactic, or other hypersensitivity reactions to chimeric or humanized antibodies or fusion proteins

  • Patients requiring treatment with a receptor activator of nuclear factor kappa-B ligand (RANKL) inhibitor (e.g. denosumab) who cannot discontinue it before treatment with atezolizumab

  • Known clinically significant liver disease, including active viral, alcoholic, or other hepatitis; cirrhosis; fatty liver; and inherited liver disease

    • Patients with past or resolved hepatitis B infection (defined as having a negative hepatitis B surface antigen [HBsAg] test and a positive anti-HBc [antibody to hepatitis B core antigen] antibody test) are eligible
    • Patients positive for hepatitis C virus (HCV) antibody are eligible only if polymerase chain reaction (PCR) is negative for HCV ribonucleic acid (RNA)
  • History or risk of autoimmune disease, including but not limited to systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, vascular thrombosis associated with antiphospholipid syndrome, Wegener's granulomatosis, Sjogren's syndrome, Guillain-Barre syndrome, multiple sclerosis, autoimmune thyroid disease, vasculitis, or glomerulonephritis (02/20/2019)

    • Patients with a history of autoimmune hypothyroidism on a stable dose of thyroid replacement hormone are eligible

    • Patients with controlled type 1 diabetes mellitus on a stable insulin regimen, or type 2 diabetes mellitus are eligible

    • Patients with eczema, psoriasis, lichen simplex chronicus or vitiligo with dermatologic manifestations only (e.g., patients with psoriatic arthritis would be excluded) are permitted provided that they meet the following conditions:

      • Patients with psoriasis must have a baseline ophthalmologic exam to rule out ocular manifestations
      • Rash must cover less than 10% of body surface area (BSA)
      • Disease is well controlled at baseline and only requiring low potency topical steroids (e.g., hydrocortisone 2.5%, hydrocortisone butyrate 0.1%, fluocinolone 0.01%, desonide 0.05%, alclometasone dipropionate 0.05%)
      • No acute exacerbations of underlying condition within the last 12 months (not requiring psoralen plus ultraviolet A radiation [PUVA], methotrexate, retinoids, biologic agents, oral calcineurin inhibitors; high potency or oral steroids)
  • History of idiopathic pulmonary fibrosis, pneumonitis (including drug induced), organizing pneumonia (i.e., bronchiolitis obliterans, cryptogenic organizing pneumonia, etc.), or evidence of active pneumonitis on screening chest computed tomography (CT) scan; history of radiation pneumonitis in the radiation field (fibrosis) is permitted

  • Patients with active tuberculosis (TB) are excluded

  • Severe infections within 4 weeks prior to cycle 1, day 1, including but not limited to hospitalization for complications of infection, bacteremia, or severe pneumonia

  • Signs or symptoms of infection within 2 weeks prior to cycle 1, day 1

  • Received oral or intravenous (IV) antibiotics within 2 weeks prior to cycle 1, day 1; patients receiving prophylactic antibiotics (e.g., for prevention of a urinary tract infection or chronic obstructive pulmonary disease) are eligible

  • Major surgical procedure within 28 days prior to cycle 1, day 1 or anticipation of need for a major surgical procedure during the course of the study

  • Administration of a live, attenuated vaccine within 4 weeks before cycle 1, day 1 or anticipation that such a live, attenuated vaccine will be required during the study and up to 5 months after the last dose of atezolizumab (06/29/2017)

    • Influenza vaccination should be given during influenza season only (approximately October to March); patients must not receive live, attenuated influenza vaccine within 4 weeks prior to cycle 1, day 1 or at any time during the study
  • Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements

  • Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial (08-JAN-2021)

  • Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 3 years, with the exception of those with a negligible risk of metastases or death, such as carcinoma in situ of the breast or cervix

  • Severe, active co-morbidity defined as follows:

    • Current (within 28 days of cycle 1, day 1) signs and/or symptoms of bowel obstruction
    • Patients who require parental hydration and/or nutrition
    • Patients who require drainage gastrostomy tube
    • Evidence of bleeding diathesis or clinically significant coagulopathy
    • Serious, non-healing or dehiscing wound, active ulcer or untreated bone fracture
    • History of hemoptysis (>= 1/2 teaspoon of bright red blood per episode) within 1 month of study enrollment
  • Significant cardiovascular or cerebrovascular disease including:

    • Uncontrolled hypertension (systolic blood pressure [SBP] >= 150 and/or diastolic blood pressure [DBP] >= 90)
    • History of myocardial infarction within 6 months
    • Unstable angina
    • New York Heart Association functional classification II, III or IV
    • Baseline ejection fraction =< 50% as assessed by echocardiogram or multi-gated acquisition (MUGA)
    • Cerebral vascular accident (CVA) or transient ischemic attack (TIA) within 6 months
    • Significant vascular disease (e.g., aortic aneurysm, requiring surgical repair or peripheral arterial thrombosis) within 6 months
  • History of abdominal/pelvic or tracheoesophageal fistula or gastrointestinal perforation and/or abdominal/pelvic abscess within 6 months prior to initiation of treatment (02/20/2019)

  • Pregnant or lactating patients

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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm III (PLD, bevacizumab)Pegylated Liposomal Doxorubicin HydrochloridePatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.
Arm I (PLD, atezolizumab)Computed TomographyPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)
Arm I (PLD, atezolizumab)Quality-of-Life AssessmentPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)
Arm I (PLD, atezolizumab)AtezolizumabPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)
Arm II (PLD, bevacizumab, atezolizumab)AtezolizumabPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo CT on study.
Arm II (PLD, bevacizumab, atezolizumab)BevacizumabPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo CT on study.
Arm II (PLD, bevacizumab, atezolizumab)Computed TomographyPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo CT on study.
Arm II (PLD, bevacizumab, atezolizumab)Quality-of-Life AssessmentPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo CT on study.
Arm III (PLD, bevacizumab)BevacizumabPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.
Arm III (PLD, bevacizumab)Computed TomographyPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.
Arm III (PLD, bevacizumab)Quality-of-Life AssessmentPatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and bevacizumab IV over 30-90 minutes on days 1 and 15. Patients also undergo CT on study.
Arm I (PLD, atezolizumab)Pegylated Liposomal Doxorubicin HydrochloridePatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1 and atezolizumab IV over 30-60 minutes on days 1 and 15. (Closed to accrual as of February 09, 2021)
Arm II (PLD, bevacizumab, atezolizumab)Pegylated Liposomal Doxorubicin HydrochloridePatients receive pegylated liposomal doxorubicin hydrochloride IV over 60 minutes on day 1, bevacizumab IV over 30-90 minutes on days 1 and 15, and atezolizumab IV over 30-60 minutes on days 1 and 15. Patients also undergo CT on study.
Primary Outcome Measures
NameTimeMethod
Progression free survival (PFS) (Phase II)From study enrollment to the investigator determined date of progression or death due to any cause, whichever occurs first, assessed up to 5 years

Will be assessed by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 criteria and will include estimates of the hazard ratios and the corresponding confidence intervals for the experimental regimen relative to the reference regimen, as well as Kaplan-Meier estimates of the survivorship function for each treatment group.

PFS (Phase III)From study enrollment to the investigator determined date of progression or death due to any cause, whichever occurs first, assessed up to 5 years

Will be assessed by RECIST v1.1 criteria and will include estimates of the hazard ratios and the corresponding confidence intervals for the experimental regimen relative to the reference regimen, as well as Kaplan-Meier estimates of the survivorship function for each treatment group.

Incidence of dose limiting toxicities (DLT) of experimental regimensUp to 28 days

Will be graded using Common Terminology Criteria for Adverse Events (CTCAE) version (v) 4.0 (CTCAE version 5.0 will be used beginning April 1, 2018). DLT will be assessed.

Overall survival (OS) (Phase III)From study enrollment to the date of death regardless of the cause, assessed up to 5 years

OS will be evaluated.

Secondary Outcome Measures
NameTimeMethod
Objective response rate (ORR) (partial or complete response) (Phase II)Up to 5 years

Will be assessed by RECIST v1.1 criteria. Will be tabulated by treatment group, and 95% confidence intervals will be presented using Wilson's Score Method. Treatment arms will be compared using a likelihood ratio chi-square test.

ORR (partial or complete response) (Phase III)Up to 5 years

Will be assessed by RECIST v1.1. Will be tabulated by treatment group, and 95% confidence intervals will be presented using Wilson's Score Method. Treatment arms will be compared using a likelihood ratio chi-square test.

Frequency and severity of adverse events (Phase II)Up to 5 years

The maximum grade of each adverse event (AE) by system organ class and Common Toxicity Criteria (CTC) 4.0 (CTCAE version 5.0 will be used beginning April 1, 2018) specific term will be tabulated for those individuals who at least initiate study treatment. The number and percent of individuals will be tabulated by the maximum grade of their AE.

Frequency and severity of adverse events (Phase III)Up to 5 years

The maximum grade of each AE by system organ class and CTC 4.0 (CTCAE version 5.0 will be used beginning April 1, 2018) specific term will be tabulated for those individuals who at least initiate study treatment. The number and percent of individuals will be tabulated by the maximum grade of their AE.

Disease-related symptoms (Phase II)Up to 2 years

Will be assessed by the National Comprehensive Cancer Network (NCCN)- Functional Assessment of Cancer Therapy (FACT) ovarian symptom index (NFOSI)-18 disease-related symptoms (DRS). A repeated measures model will be used to estimate and compare the mean DRS-physical (P) scores for the treatment groups. Model covariates will include the patients' randomly assigned study treatment, age at enrollment onto the study, initial performance status, pre-treatment DRS-P score, assessment time and treatment-by-time interaction. The primary analyses will include only those treatments selected at the end of the phase II study and all of the patients assigned to one of these treatments during either stage 2 of the safety lead-in, phase II or phase III component of the study regardless of their compliance with the study treatment or eligibility status, provided at least one baseline (pre-treatment) and one follow-up assessment is available.

Disease-related symptoms (Phase III)Up to 2 years

Will be assessed by the NFOSI-18 DRS. A repeated measures model will be used to estimate and compare the mean DRS-P scores for the treatment groups. Model covariates will include the patients' randomly assigned study treatment, age at enrollment onto the study, initial performance status, pre-treatment DRS-P score, assessment time and treatment-by-time interaction. The primary analyses will include only those treatments selected at the end of the phase II study and all of the patients assigned to one of these treatments during either stage 2 of the safety lead-in, phase II or phase III component of the study regardless of their compliance with the study treatment or eligibility status, provided at least one baseline (pre-treatment) and one follow-up assessment is available.

Patient reported outcomes (PRO) (Phase II)Up to 2 years

Will be as measured by treatment side effects (TSE), function/well-being (FWB), fatigue and health status. Each of the other general PRO scales will be analyzed with repeated measures models. Exploratory analyses will include an assessment of the model residuals in order to evaluate the adequacy of modeling assumptions. Additional descriptive analyses will assess whether the differences in mean scores between groups vary systematically with time in a linear or quadratic fashion.

PD-L1 expressionUp to 5 years

Will be assessed in enrolled patients using immunohistochemistry on tumors embedded in paraffin. The proportion of patients expressing PD-L1 in this patient population will be estimated. A proportional hazards model will be used to estimate the hazard of death for patients who express PD-L1 relative to those who do not express PL-D1 for each treatment group. The homogeneity of these estimated hazard ratios will then be assessed. Its association with the duration of PFS or OS will be determined.

Patient reported outcomes (Phase III)Up to 2 years

Will be measured by TSE, FWB, fatigue and health status. Each of the other general PRO scales will be analyzed with repeated measures models. Exploratory analyses will include an assessment of the model residuals in order to evaluate the adequacy of modeling assumptions. Additional descriptive analyses will assess whether the differences in mean scores between groups vary systematically with time in a linear or quadratic fashion.

Trial Locations

Locations (926)

Contra Costa Regional Medical Center

🇺🇸

Martinez, California, United States

Kaiser San Rafael-Gallinas

🇺🇸

San Rafael, California, United States

Kaiser Permanente- Marshall Medical Offices

🇺🇸

Redwood City, California, United States

Sutter Solano Medical Center/Cancer Center

🇺🇸

Vallejo, California, United States

Illinois CancerCare-Carthage

🇺🇸

Carthage, Illinois, United States

Saint Luke's Cancer Institute - Nampa

🇺🇸

Nampa, Idaho, United States

North Shore Medical Center

🇺🇸

Skokie, Illinois, United States

Mercy Hospital Joplin

🇺🇸

Joplin, Missouri, United States

Main Line Health Center-Collegeville

🇺🇸

Collegeville, Pennsylvania, United States

Dayton Physicians LLC-Wayne

🇺🇸

Greenville, Ohio, United States

Geisinger Medical Group

🇺🇸

State College, Pennsylvania, United States

Vince Lombardi Cancer Clinic - Oshkosh

🇺🇸

Oshkosh, Wisconsin, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

Kaiser Permanente Los Angeles Medical Center

🇺🇸

Los Angeles, California, United States

Kaiser Permanente West Los Angeles

🇺🇸

Los Angeles, California, United States

Emory University Hospital Midtown

🇺🇸

Atlanta, Georgia, United States

Northside Hospital

🇺🇸

Atlanta, Georgia, United States

Greater Baltimore Medical Center

🇺🇸

Baltimore, Maryland, United States

Kaiser Permanente-Woodlawn Medical Center

🇺🇸

Baltimore, Maryland, United States

Allegheny General Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

University of Pittsburgh Cancer Institute (UPCI)

🇺🇸

Pittsburgh, Pennsylvania, United States

Queen's Medical Center

🇺🇸

Honolulu, Hawaii, United States

Rush University Medical Center

🇺🇸

Chicago, Illinois, United States

Northwestern University

🇺🇸

Chicago, Illinois, United States

University of Illinois

🇺🇸

Chicago, Illinois, United States

John H Stroger Jr Hospital of Cook County

🇺🇸

Chicago, Illinois, United States

University of Chicago Comprehensive Cancer Center

🇺🇸

Chicago, Illinois, United States

Cleveland Clinic Foundation

🇺🇸

Cleveland, Ohio, United States

Centro de Hematologia y Oncologia del Sur

🇵🇷

Santa Isabel, Puerto Rico

FHCC South Lake Union

🇺🇸

Seattle, Washington, United States

Fred Hutchinson Cancer Research Center

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Cherry Hill

🇺🇸

Seattle, Washington, United States

Indiana University/Melvin and Bren Simon Cancer Center

🇺🇸

Indianapolis, Indiana, United States

Franciscan Health Indianapolis

🇺🇸

Indianapolis, Indiana, United States

Ben Taub General Hospital

🇺🇸

Houston, Texas, United States

Houston Methodist Hospital

🇺🇸

Houston, Texas, United States

Methodist Willowbrook Hospital

🇺🇸

Houston, Texas, United States

Houston Methodist West Hospital

🇺🇸

Houston, Texas, United States

Kaiser Permanente-San Diego Mission

🇺🇸

San Diego, California, United States

OptumCare Cancer Care at Charleston

🇺🇸

Las Vegas, Nevada, United States

Cancer and Blood Specialists-Shadow

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Central

🇺🇸

Las Vegas, Nevada, United States

Women's Cancer Center of Nevada

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Prostate Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast

🇺🇸

Las Vegas, Nevada, United States

Ann M Wierman MD LTD

🇺🇸

Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Cathedral Rock

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Smoke Ranch

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

Alliance for Childhood Diseases/Cure 4 the Kids Foundation

🇺🇸

Las Vegas, Nevada, United States

Summerlin Hospital Medical Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

🇺🇸

Las Vegas, Nevada, United States

Good Samaritan Hospital - Cincinnati

🇺🇸

Cincinnati, Ohio, United States

Bethesda North Hospital

🇺🇸

Cincinnati, Ohio, United States

Providence Alaska Medical Center

🇺🇸

Anchorage, Alaska, United States

Alaska Women's Cancer Care

🇺🇸

Anchorage, Alaska, United States

Epic Care Partners in Cancer Care

🇺🇸

Emeryville, California, United States

Marin General Hospital

🇺🇸

Greenbrae, California, United States

Kaiser Permanente - Harbor City

🇺🇸

Harbor City, California, United States

Boulder Community Foothills Hospital

🇺🇸

Boulder, Colorado, United States

Mountain Blue Cancer Care Center - Swedish

🇺🇸

Englewood, Colorado, United States

Saint Anthony Hospital

🇺🇸

Lakewood, Colorado, United States

McKee Medical Center

🇺🇸

Loveland, Colorado, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Saint Luke's Cancer Institute - Twin Falls

🇺🇸

Twin Falls, Idaho, United States

Parker Adventist Hospital

🇺🇸

Parker, Colorado, United States

Northwestern Medicine Cancer Center Warrenville

🇺🇸

Warrenville, Illinois, United States

Ascension Saint Vincent Indianapolis Hospital

🇺🇸

Indianapolis, Indiana, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Springfield Clinic

🇺🇸

Springfield, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

Saint Luke's Cancer Institute - Meridian

🇺🇸

Meridian, Idaho, United States

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

NorthShore University HealthSystem-Highland Park Hospital

🇺🇸

Highland Park, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

SIH Cancer Institute

🇺🇸

Carterville, Illinois, United States

Reid Health

🇺🇸

Richmond, Indiana, United States

Midwestern Regional Medical Center

🇺🇸

Zion, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Kaiser Permanente - Kensington Medical Center

🇺🇸

Kensington, Maryland, United States

Maine Medical Center- Scarborough Campus

🇺🇸

Scarborough, Maine, United States

Medical Oncology and Hematology Associates-West Des Moines

🇺🇸

Clive, Iowa, United States

Alegent Health Mercy Hospital

🇺🇸

Council Bluffs, Iowa, United States

Saint Alphonsus Cancer Care Center-Nampa

🇺🇸

Nampa, Idaho, United States

Union Hospital

🇺🇸

Terre Haute, Indiana, United States

Memorial Hospital of Carbondale

🇺🇸

Carbondale, Illinois, United States

University of Chicago Medicine-Orland Park

🇺🇸

Orland Park, Illinois, United States

Southwest Illinois Health Services LLP

🇺🇸

Swansea, Illinois, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

Coffeyville Regional Medical Center

🇺🇸

Coffeyville, Kansas, United States

NorthShore University HealthSystem-Evanston Hospital

🇺🇸

Evanston, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

Baptist Health Paducah

🇺🇸

Paducah, Kentucky, United States

Mary Bird Perkins Cancer Center

🇺🇸

Baton Rouge, Louisiana, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Olathe Health Cancer Center

🇺🇸

Olathe, Kansas, United States

Methodist Medical Center of Illinois

🇺🇸

Peoria, Illinois, United States

Lawrence Memorial Hospital

🇺🇸

Lawrence, Kansas, United States

Illinois CancerCare - Washington

🇺🇸

Washington, Illinois, United States

UC Comprehensive Cancer Center at Silver Cross

🇺🇸

New Lenox, Illinois, United States

Parkview Hospital Randallia

🇺🇸

Fort Wayne, Indiana, United States

Central Care Cancer Center - Great Bend

🇺🇸

Great Bend, Kansas, United States

Baptist Health Madisonville/Merle Mahr Cancer Center

🇺🇸

Madisonville, Kentucky, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Saint Elizabeth Healthcare Edgewood

🇺🇸

Edgewood, Kentucky, United States

Associates In Womens Health

🇺🇸

Wichita, Kansas, United States

University of Iowa/Holden Comprehensive Cancer Center

🇺🇸

Iowa City, Iowa, United States

Salina Regional Health Center

🇺🇸

Salina, Kansas, United States

Cotton O'Neil Cancer Center / Stormont Vail Health

🇺🇸

Topeka, Kansas, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

Franciscan Saint Elizabeth Health - Lafayette East

🇺🇸

Lafayette, Indiana, United States

University of Kansas Hospital-Indian Creek Campus

🇺🇸

Overland Park, Kansas, United States

Baton Rouge General Medical Center

🇺🇸

Baton Rouge, Louisiana, United States

Saint Joseph London

🇺🇸

London, Kentucky, United States

Greater Regional Medical Center

🇺🇸

Creston, Iowa, United States

Ochsner High Grove

🇺🇸

Baton Rouge, Louisiana, United States

University of Kansas Cancer Center-Overland Park

🇺🇸

Overland Park, Kansas, United States

Trinity Health IHA Medical Group Hematology Oncology - Canton

🇺🇸

Canton, Michigan, United States

Lafayette Family Cancer Center-EMMC

🇺🇸

Brewer, Maine, United States

Kaiser Permanente-Gaithersburg Medical Center

🇺🇸

Gaithersburg, Maryland, United States

Ascension Via Christi - Pittsburg

🇺🇸

Pittsburg, Kansas, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

Baptist Health Corbin

🇺🇸

Corbin, Kentucky, United States

Hematology/Oncology Clinic PLLC

🇺🇸

Baton Rouge, Louisiana, United States

Medical Center of Baton Rouge

🇺🇸

Baton Rouge, Louisiana, United States

Johns Hopkins University/Sidney Kimmel Cancer Center

🇺🇸

Baltimore, Maryland, United States

Spectrum Health at Butterworth Campus

🇺🇸

Grand Rapids, Michigan, United States

Commonwealth Cancer Center-Corbin

🇺🇸

Corbin, Kentucky, United States

Saint Joseph Mercy Brighton

🇺🇸

Brighton, Michigan, United States

Jewish Hospital Medical Center South

🇺🇸

Shepherdsville, Kentucky, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Lahey Hospital and Medical Center

🇺🇸

Burlington, Massachusetts, United States

Genesee Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Sparrow Hospital

🇺🇸

Lansing, Michigan, United States

Great Lakes Cancer Management Specialists-Doctors Park

🇺🇸

East China Township, Michigan, United States

Allegiance Health

🇺🇸

Jackson, Michigan, United States

University of Maryland Shore Medical Center at Easton

🇺🇸

Easton, Maryland, United States

Saint Mary's Oncology/Hematology Associates of Marlette

🇺🇸

Marlette, Michigan, United States

Eastern Maine Medical Center

🇺🇸

Bangor, Maine, United States

Genesee Cancer and Blood Disease Treatment Center

🇺🇸

Flint, Michigan, United States

Academic Hematology Oncology Specialists

🇺🇸

Grosse Pointe Woods, Michigan, United States

Helen DeVos Children's Hospital at Spectrum Health

🇺🇸

Grand Rapids, Michigan, United States

Kaiser Permanente - Largo Medical Center

🇺🇸

Largo, Maryland, United States

Caro Cancer Center

🇺🇸

Caro, Michigan, United States

Trinity Health Grand Rapids Hospital

🇺🇸

Grand Rapids, Michigan, United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

🇺🇸

Grosse Pointe Woods, Michigan, United States

Michigan Breast Specialists-Grosse Pointe Woods

🇺🇸

Grosse Pointe Woods, Michigan, United States

Sanford Cancer Center Worthington

🇺🇸

Worthington, Minnesota, United States

Lakeland Hospital Niles

🇺🇸

Niles, Michigan, United States

CHI Health Good Samaritan

🇺🇸

Kearney, Nebraska, United States

Sanford Thief River Falls Medical Center

🇺🇸

Thief River Falls, Minnesota, United States

Parkland Health Center-Bonne Terre

🇺🇸

Bonne Terre, Missouri, United States

Las Vegas Urology - Pecos

🇺🇸

Las Vegas, Nevada, United States

Lakeview Hospital

🇺🇸

Stillwater, Minnesota, United States

Cancer and Blood Specialists-Henderson

🇺🇸

Henderson, Nevada, United States

Fairview Lakes Medical Center

🇺🇸

Wyoming, Minnesota, United States

Parkland Health Center - Farmington

🇺🇸

Farmington, Missouri, United States

Capital Region Southwest Campus

🇺🇸

Jefferson City, Missouri, United States

Comprehensive Cancer Centers of Nevada - Henderson

🇺🇸

Henderson, Nevada, United States

Carson Tahoe Regional Medical Center

🇺🇸

Carson City, Nevada, United States

Urology Specialists of Nevada - Green Valley

🇺🇸

Henderson, Nevada, United States

Desert West Surgery

🇺🇸

Las Vegas, Nevada, United States

Midlands Community Hospital

🇺🇸

Papillion, Nebraska, United States

GenesisCare USA - Las Vegas

🇺🇸

Las Vegas, Nevada, United States

Saint Louis Cancer and Breast Institute-Ballwin

🇺🇸

Ballwin, Missouri, United States

University of Kansas Cancer Center at North Kansas City Hospital

🇺🇸

North Kansas City, Missouri, United States

OptumCare Cancer Care at Seven Hills

🇺🇸

Henderson, Nevada, United States

University Medical Center of Southern Nevada

🇺🇸

Las Vegas, Nevada, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Southeast Cancer Center

🇺🇸

Cape Girardeau, Missouri, United States

Las Vegas Urology - Pebble

🇺🇸

Henderson, Nevada, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

Saint Elizabeth Regional Medical Center

🇺🇸

Lincoln, Nebraska, United States

Comprehensive Cancer Centers of Nevada-Horizon Ridge

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson

🇺🇸

Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson

🇺🇸

Henderson, Nevada, United States

Las Vegas Urology - Green Valley

🇺🇸

Henderson, Nevada, United States

Las Vegas Urology - Sunset

🇺🇸

Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at MountainView

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Town Center

🇺🇸

Las Vegas, Nevada, United States

The Valley Hospital-Luckow Pavilion

🇺🇸

Paramus, New Jersey, United States

Valley Medical Group - Wayne Multispecialty Practice

🇺🇸

Wayne, New Jersey, United States

Memorial Sloan Kettering Monmouth

🇺🇸

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen

🇺🇸

Montvale, New Jersey, United States

Valley Hospital

🇺🇸

Ridgewood, New Jersey, United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

🇺🇸

Lebanon, New Hampshire, United States

Rutgers Cancer Institute of New Jersey

🇺🇸

New Brunswick, New Jersey, United States

Hope Cancer Care of Nevada-Pahrump

🇺🇸

Pahrump, Nevada, United States

Saint Mary's Regional Medical Center

🇺🇸

Reno, Nevada, United States

AtlantiCare Health Park-Cape May Court House

🇺🇸

Cape May Court House, New Jersey, United States

GenesisCare USA - Fort Apache

🇺🇸

Las Vegas, Nevada, United States

University Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Presbyterian Rust Medical Center/Jorgensen Cancer Center

🇺🇸

Rio Rancho, New Mexico, United States

Memorial Sloan Kettering Westchester

🇺🇸

Harrison, New York, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Memorial Sloan Kettering Nassau

🇺🇸

Uniondale, New York, United States

Mount Sinai Chelsea

🇺🇸

New York, New York, United States

Dartmouth Cancer Center - Nashua

🇺🇸

Nashua, New Hampshire, United States

Lenox Hill Hospital

🇺🇸

New York, New York, United States

Renown Regional Medical Center

🇺🇸

Reno, Nevada, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Grandview Hospital

🇺🇸

Dayton, Ohio, United States

Wayne Memorial Hospital

🇺🇸

Goldsboro, North Carolina, United States

Aultman Health Foundation

🇺🇸

Canton, Ohio, United States

Aultman Alliance Community Hospital

🇺🇸

Alliance, Ohio, United States

Geauga Hospital

🇺🇸

Chardon, Ohio, United States

Laura and Isaac Perlmutter Cancer Center at NYU Langone

🇺🇸

New York, New York, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

Oncology Hematology Care Inc-Kenwood

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside

🇺🇸

Cincinnati, Ohio, United States

Carolinas Medical Center/Levine Cancer Institute

🇺🇸

Charlotte, North Carolina, United States

Dayton Physicians LLC-Miami Valley South

🇺🇸

Centerville, Ohio, United States

Mount Sinai Hospital

🇺🇸

New York, New York, United States

Miami Valley Hospital South

🇺🇸

Centerville, Ohio, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Atrium Health Cabarrus/LCI-Concord

🇺🇸

Concord, North Carolina, United States

Cone Health Cancer Center at Alamance Regional

🇺🇸

Burlington, North Carolina, United States

MetroHealth Medical Center

🇺🇸

Cleveland, Ohio, United States

Good Samaritan Hospital - Dayton

🇺🇸

Dayton, Ohio, United States

Margaret R Pardee Memorial Hospital

🇺🇸

Hendersonville, North Carolina, United States

UHHS-Chagrin Highlands Medical Center

🇺🇸

Beachwood, Ohio, United States

Indu and Raj Soin Medical Center

🇺🇸

Beavercreek, Ohio, United States

Cone Heath Cancer Center at Mebane

🇺🇸

Mebane, North Carolina, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

Atrium Medical Center-Middletown Regional Hospital

🇺🇸

Franklin, Ohio, United States

Kettering Medical Center

🇺🇸

Kettering, Ohio, United States

TriHealth Cancer Institute-Anderson

🇺🇸

Cincinnati, Ohio, United States

Novant Health Cancer Institute - Kernersville

🇺🇸

Kernersville, North Carolina, United States

Duke Raleigh Hospital

🇺🇸

Raleigh, North Carolina, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

Dayton Physician LLC-Miami Valley Hospital North

🇺🇸

Dayton, Ohio, United States

Newark Radiation Oncology

🇺🇸

Newark, Ohio, United States

Clackamas Radiation Oncology Center

🇺🇸

Clackamas, Oregon, United States

Providence Cancer Institute Clackamas Clinic

🇺🇸

Clackamas, Oregon, United States

Bryn Mawr Hospital

🇺🇸

Bryn Mawr, Pennsylvania, United States

Saint Rita's Medical Center

🇺🇸

Lima, Ohio, United States

Springfield Regional Cancer Center

🇺🇸

Springfield, Ohio, United States

UHHS-Westlake Medical Center

🇺🇸

Westlake, Ohio, United States

Legacy Mount Hood Medical Center

🇺🇸

Gresham, Oregon, United States

Saint Joseph Warren Hospital

🇺🇸

Warren, Ohio, United States

Adams Cancer Center

🇺🇸

Gettysburg, Pennsylvania, United States

Upper Valley Medical Center

🇺🇸

Troy, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

Mount Carmel Grove City Hospital

🇺🇸

Grove City, Ohio, United States

Bay Area Hospital

🇺🇸

Coos Bay, Oregon, United States

Ephrata Cancer Center

🇺🇸

Ephrata, Pennsylvania, United States

Dublin Methodist Hospital

🇺🇸

Dublin, Ohio, United States

Saint Vincent Mercy Medical Center

🇺🇸

Toledo, Ohio, United States

Fairfield Medical Center

🇺🇸

Lancaster, Ohio, United States

UH Seidman Cancer Center at Southwest General Hospital

🇺🇸

Middleburg Heights, Ohio, United States

Chambersburg Hospital

🇺🇸

Chambersburg, Pennsylvania, United States

Lehigh Valley Hospital-Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Saint Alphonsus Medical Center-Ontario

🇺🇸

Ontario, Oregon, United States

Main Line Health Center-Exton

🇺🇸

Exton, Pennsylvania, United States

Dayton Physicians LLC-Atrium

🇺🇸

Franklin, Ohio, United States

Wayne Hospital

🇺🇸

Greenville, Ohio, United States

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

🇺🇸

Toledo, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

Springfield Regional Medical Center

🇺🇸

Springfield, Ohio, United States

Jefferson Hospital

🇺🇸

Jefferson Hills, Pennsylvania, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus

🇺🇸

Mentor, Ohio, United States

Geisinger Medical Center-Cancer Center Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

ProMedica Flower Hospital

🇺🇸

Sylvania, Ohio, United States

Saint Elizabeth Youngstown Hospital

🇺🇸

Youngstown, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

MGC Hematology Oncology-Union

🇺🇸

Union, South Carolina, United States

Legacy Meridian Park Hospital

🇺🇸

Tualatin, Oregon, United States

Medical Center Clinic-New Castle Office

🇺🇸

New Castle, Pennsylvania, United States

Wexford Health and Wellness Pavilion

🇺🇸

Wexford, Pennsylvania, United States

Memorial Hospital

🇺🇸

Chattanooga, Tennessee, United States

Pulmonary Medicine Center of Chattanooga-Hixson

🇺🇸

Hixson, Tennessee, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

West Penn Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

University of Virginia Cancer Center

🇺🇸

Charlottesville, Virginia, United States

Spartanburg Medical Center

🇺🇸

Spartanburg, South Carolina, United States

Lancaster General Ann B Barshinger Cancer Institute

🇺🇸

Lancaster, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg

🇺🇸

Lewisburg, Pennsylvania, United States

Harrison Medical Center

🇺🇸

Bremerton, Washington, United States

Riddle Memorial Hospital

🇺🇸

Media, Pennsylvania, United States

Carilion Clinic Gynecological Oncology

🇺🇸

Roanoke, Virginia, United States

Providence Regional Cancer Partnership

🇺🇸

Everett, Washington, United States

Northwest Cancer Clinic

🇺🇸

Kennewick, Washington, United States

Chester County Hospital

🇺🇸

West Chester, Pennsylvania, United States

Saint Francis Hospital

🇺🇸

Federal Way, Washington, United States

Wellmont Medical Associates Oncology and Hematology-Johnson City

🇺🇸

Johnson City, Tennessee, United States

WellSpan Health-York Hospital

🇺🇸

York, Pennsylvania, United States

University of Pennsylvania/Abramson Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

Inova Fairfax Hospital

🇺🇸

Falls Church, Virginia, United States

Valley Medical Center

🇺🇸

Renton, Washington, United States

Sechler Family Cancer Center

🇺🇸

Lebanon, Pennsylvania, United States

Virginia Mason Bainbridge Island Medical Center

🇺🇸

Bainbridge Island, Washington, United States

Virginia Mason Federal Way Medical Center

🇺🇸

Federal Way, Washington, United States

WellSpan Health-York Cancer Center

🇺🇸

York, Pennsylvania, United States

Women and Infants Hospital

🇺🇸

Providence, Rhode Island, United States

Houston Methodist The Woodlands Hospital

🇺🇸

The Woodlands, Texas, United States

Wellmont Medical Associates-Bristol

🇺🇸

Bristol, Virginia, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

Vanderbilt-Ingram Cancer Center Cool Springs

🇺🇸

Franklin, Tennessee, United States

Gibbs Cancer Center-Pelham

🇺🇸

Greer, South Carolina, United States

Paoli Memorial Hospital

🇺🇸

Paoli, Pennsylvania, United States

Reading Hospital

🇺🇸

West Reading, Pennsylvania, United States

Ballad Health Cancer Care - Kingsport

🇺🇸

Kingsport, Tennessee, United States

UT Southwestern/Simmons Cancer Center-Dallas

🇺🇸

Dallas, Texas, United States

Avera Cancer Institute

🇺🇸

Sioux Falls, South Dakota, United States

Rapid City Regional Hospital

🇺🇸

Rapid City, South Dakota, United States

Providence Regional Cancer System-Centralia

🇺🇸

Centralia, Washington, United States

Peninsula Cancer Center

🇺🇸

Poulsbo, Washington, United States

Gibbs Cancer Center-Gaffney

🇺🇸

Gaffney, South Carolina, United States

Southwest VA Regional Cancer Center

🇺🇸

Norton, Virginia, United States

Providence Regional Cancer System-Aberdeen

🇺🇸

Aberdeen, Washington, United States

Saint Elizabeth Hospital

🇺🇸

Enumclaw, Washington, United States

MultiCare Gig Harbor Medical Park

🇺🇸

Gig Harbor, Washington, United States

Houston Methodist Sugar Land Hospital

🇺🇸

Sugar Land, Texas, United States

MultiCare Good Samaritan Hospital

🇺🇸

Puyallup, Washington, United States

Kadlec Clinic Hematology and Oncology

🇺🇸

Kennewick, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

🇺🇸

Poulsbo, Washington, United States

Kaiser Permanente Tysons Corner Medical Center

🇺🇸

McLean, Virginia, United States

Saint Clare Hospital

🇺🇸

Lakewood, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Puyallup

🇺🇸

Puyallup, Washington, United States

Highline Medical Center-Main Campus

🇺🇸

Burien, Washington, United States

MultiCare Auburn Medical Center

🇺🇸

Auburn, Washington, United States

Inova Schar Cancer Institute

🇺🇸

Fairfax, Virginia, United States

Doctor's Cancer Center-Arecibo

🇵🇷

Arecibo, Puerto Rico

Instituto Oncologia Moderna Ponce

🇵🇷

Ponce, Puerto Rico

Kaiser Permanente Washington

🇺🇸

Seattle, Washington, United States

San Juan City Hospital

🇵🇷

San Juan, Puerto Rico

San Juan Community Oncology Group

🇵🇷

San Juan, Puerto Rico

Centro Comprensivo de Cancer de UPR

🇵🇷

San Juan, Puerto Rico

Marshfield Clinic - Ladysmith Center

🇺🇸

Ladysmith, Wisconsin, United States

Cancer Center-Metro Medical Center Bayamon

🇵🇷

Bayamon, Puerto Rico

HIMA San Pablo Oncologic Hospital

🇵🇷

Caguas, Puerto Rico

Hematologia Oncologia San Pablo

🇵🇷

Bayamon, Puerto Rico

Primary Care Physician Group

🇵🇷

San Juan, Puerto Rico

California Pacific Medical Center-Pacific Campus

🇺🇸

San Francisco, California, United States

Kaiser Permanente-San Francisco

🇺🇸

San Francisco, California, United States

UCSF Medical Center-Mission Bay

🇺🇸

San Francisco, California, United States

Kaiser Permanente San Leandro

🇺🇸

San Leandro, California, United States

Abbott-Northwestern Hospital

🇺🇸

Minneapolis, Minnesota, United States

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Health Partners Inc

🇺🇸

Minneapolis, Minnesota, United States

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

Washington University School of Medicine

🇺🇸

Saint Louis, Missouri, United States

Baystate Medical Center

🇺🇸

Springfield, Massachusetts, United States

Billings Clinic-Cody

🇺🇸

Cody, Wyoming, United States

Welch Cancer Center

🇺🇸

Sheridan, Wyoming, United States

University of Rochester

🇺🇸

Rochester, New York, United States

Cheyenne Regional Medical Center-West

🇺🇸

Cheyenne, Wyoming, United States

Vanderbilt Breast Center at One Hundred Oaks

🇺🇸

Nashville, Tennessee, United States

Vanderbilt University/Ingram Cancer Center

🇺🇸

Nashville, Tennessee, United States

Cancer Center at Saint Joseph's

🇺🇸

Phoenix, Arizona, United States

Wayne State University/Karmanos Cancer Institute

🇺🇸

Detroit, Michigan, United States

Henry Ford Hospital

🇺🇸

Detroit, Michigan, United States

Ascension Saint John Hospital

🇺🇸

Detroit, Michigan, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

Danbury Hospital

🇺🇸

Danbury, Connecticut, United States

Swedish Medical Center

🇺🇸

Englewood, Colorado, United States

University of Mississippi Medical Center

🇺🇸

Jackson, Mississippi, United States

Saint Patrick Hospital - Community Hospital

🇺🇸

Missoula, Montana, United States

Cancer Treatment Centers of America

🇺🇸

Tulsa, Oklahoma, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

Benefis Healthcare- Sletten Cancer Institute

🇺🇸

Great Falls, Montana, United States

Lancaster General Hospital

🇺🇸

Lancaster, Pennsylvania, United States

Saint Vincent Frontier Cancer Center

🇺🇸

Billings, Montana, United States

Community Medical Hospital

🇺🇸

Missoula, Montana, United States

Nebraska Methodist Hospital

🇺🇸

Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Hematology and Oncology Consultants PC

🇺🇸

Omaha, Nebraska, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

University of Nebraska Medical Center

🇺🇸

Omaha, Nebraska, United States

Legacy Good Samaritan Hospital and Medical Center

🇺🇸

Portland, Oregon, United States

Providence Portland Medical Center

🇺🇸

Portland, Oregon, United States

Providence Saint Vincent Medical Center

🇺🇸

Portland, Oregon, United States

Aurora Saint Luke's Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Cancer Center of Colorado at Sloan's Lake

🇺🇸

Denver, Colorado, United States

Denver Health Medical Center

🇺🇸

Denver, Colorado, United States

Kaiser Permanente-Franklin

🇺🇸

Denver, Colorado, United States

National Jewish Health-Main Campus

🇺🇸

Denver, Colorado, United States

The Women's Imaging Center

🇺🇸

Denver, Colorado, United States

Colorado Blood Cancer Institute

🇺🇸

Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One

🇺🇸

Denver, Colorado, United States

Porter Adventist Hospital

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown

🇺🇸

Denver, Colorado, United States

SCL Health Saint Joseph Hospital

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose

🇺🇸

Denver, Colorado, United States

Rose Medical Center

🇺🇸

Denver, Colorado, United States

Western Surgical Care

🇺🇸

Denver, Colorado, United States

Delbert Day Cancer Institute at PCRMC

🇺🇸

Rolla, Missouri, United States

Saint Louis Cancer and Breast Institute-South City

🇺🇸

Saint Louis, Missouri, United States

National Jewish Health-Western Hematology Oncology

🇺🇸

Golden, Colorado, United States

Manhattan Eye Ear and Throat Hospital

🇺🇸

New York, New York, United States

Memorial Sloan Kettering Cancer Center

🇺🇸

New York, New York, United States

SUNY Upstate Medical Center-Community Campus

🇺🇸

Syracuse, New York, United States

Wellmont Holston Valley Hospital and Medical Center

🇺🇸

Kingsport, Tennessee, United States

Memorial GYN Plus

🇺🇸

Ooltewah, Tennessee, United States

Thompson Cancer Survival Center

🇺🇸

Knoxville, Tennessee, United States

Cone Health Cancer Center

🇺🇸

Greensboro, North Carolina, United States

Novant Health Presbyterian Medical Center Huntersville

🇺🇸

Huntersville, North Carolina, United States

Novant Health Cancer Institute - Wilkesboro

🇺🇸

Wilkesboro, North Carolina, United States

Annie Penn Memorial Hospital

🇺🇸

Reidsville, North Carolina, United States

Novant Health Cancer Institute - Thomasville

🇺🇸

Thomasville, North Carolina, United States

Novant Health New Hanover Regional Medical Center

🇺🇸

Wilmington, North Carolina, United States

Las Vegas Cancer Center-Medical Center

🇺🇸

Las Vegas, Nevada, United States

Weisberg Cancer Treatment Center

🇺🇸

Farmington Hills, Michigan, United States

Saint Joseph Mercy Oakland

🇺🇸

Pontiac, Michigan, United States

Helen F Graham Cancer Center

🇺🇸

Newark, Delaware, United States

Marshfield Medical Center - Weston

🇺🇸

Weston, Wisconsin, United States

Saint Anthony's Health

🇺🇸

Alton, Illinois, United States

Providence Newberg Medical Center

🇺🇸

Newberg, Oregon, United States

Forbes Hospital

🇺🇸

Monroeville, Pennsylvania, United States

Bozeman Deaconess Hospital

🇺🇸

Bozeman, Montana, United States

Carle at The Riverfront

🇺🇸

Danville, Illinois, United States

Island Urology

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Cenrer - POB I

🇺🇸

Honolulu, Hawaii, United States

Straub Clinic and Hospital

🇺🇸

Honolulu, Hawaii, United States

University of Hawaii Cancer Center

🇺🇸

Honolulu, Hawaii, United States

Hawaii Cancer Care Inc-Liliha

🇺🇸

Honolulu, Hawaii, United States

Ochsner Baptist Medical Center

🇺🇸

New Orleans, Louisiana, United States

Virginia Gynecologic Oncology

🇺🇸

Richmond, Virginia, United States

Ochsner Medical Center Jefferson

🇺🇸

New Orleans, Louisiana, United States

Southeastern Medical Oncology Center-Jacksonville

🇺🇸

Jacksonville, North Carolina, United States

Kaiser Permanente Downtown Commons

🇺🇸

Sacramento, California, United States

Mercy Cancer Center - Sacramento

🇺🇸

Sacramento, California, United States

Kaiser Permanente-South Sacramento

🇺🇸

Sacramento, California, United States

Sutter Medical Center Sacramento

🇺🇸

Sacramento, California, United States

Kaiser Permanente - Sacramento

🇺🇸

Sacramento, California, United States

Rocky Mountain Cancer Centers-Aurora

🇺🇸

Aurora, Colorado, United States

The Medical Center of Aurora

🇺🇸

Aurora, Colorado, United States

UCHealth University of Colorado Hospital

🇺🇸

Aurora, Colorado, United States

Saint Joseph Mercy Hospital

🇺🇸

Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center

🇺🇸

Ann Arbor, Michigan, United States

Novant Health Forsyth Medical Center

🇺🇸

Winston-Salem, North Carolina, United States

Novant Health Oncology Specialists

🇺🇸

Winston-Salem, North Carolina, United States

Anchorage Associates in Radiation Medicine

🇺🇸

Anchorage, Alaska, United States

Anchorage Radiation Therapy Center

🇺🇸

Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC

🇺🇸

Anchorage, Alaska, United States

Katmai Oncology Group

🇺🇸

Anchorage, Alaska, United States

Anchorage Oncology Centre

🇺🇸

Anchorage, Alaska, United States

Fairbanks Memorial Hospital

🇺🇸

Fairbanks, Alaska, United States

Mercy Hospital Fort Smith

🇺🇸

Fort Smith, Arkansas, United States

Banner University Medical Center - Tucson

🇺🇸

Tucson, Arizona, United States

Kingman Regional Medical Center

🇺🇸

Kingman, Arizona, United States

CTCA at Western Regional Medical Center

🇺🇸

Goodyear, Arizona, United States

CHI Saint Vincent Cancer Center Hot Springs

🇺🇸

Hot Springs, Arkansas, United States

Kaiser Permanente-Anaheim

🇺🇸

Anaheim, California, United States

Kaiser Permanente-Deer Valley Medical Center

🇺🇸

Antioch, California, United States

University of Arkansas for Medical Sciences

🇺🇸

Little Rock, Arkansas, United States

Mission Hope Medical Oncology - Arroyo Grande

🇺🇸

Arroyo Grande, California, United States

PCR Oncology

🇺🇸

Arroyo Grande, California, United States

Kaiser Permanente-Baldwin Park

🇺🇸

Baldwin Park, California, United States

Sutter Cancer Centers Radiation Oncology Services-Auburn

🇺🇸

Auburn, California, United States

Sutter Auburn Faith Hospital

🇺🇸

Auburn, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center

🇺🇸

Burbank, California, United States

Kaiser Permanente-Bellflower

🇺🇸

Bellflower, California, United States

Alta Bates Summit Medical Center-Herrick Campus

🇺🇸

Berkeley, California, United States

Mills-Peninsula Medical Center

🇺🇸

Burlingame, California, United States

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

🇺🇸

Cameron Park, California, United States

Mercy San Juan Medical Center

🇺🇸

Carmichael, California, United States

Community Cancer Institute

🇺🇸

Clovis, California, United States

Eden Hospital Medical Center

🇺🇸

Castro Valley, California, United States

Kaiser Permanente Dublin

🇺🇸

Dublin, California, United States

Sutter Davis Hospital

🇺🇸

Davis, California, United States

Mercy Cancer Center - Elk Grove

🇺🇸

Elk Grove, California, United States

University Oncology Associates

🇺🇸

Clovis, California, United States

John Muir Medical Center-Concord Campus

🇺🇸

Concord, California, United States

Epic Care-Dublin

🇺🇸

Dublin, California, United States

Bay Area Breast Surgeons Inc

🇺🇸

Emeryville, California, United States

Kaiser Permanente-Fontana

🇺🇸

Fontana, California, United States

Kaiser Permanente-Fremont

🇺🇸

Fremont, California, United States

Palo Alto Medical Foundation-Fremont

🇺🇸

Fremont, California, United States

Fresno Cancer Center

🇺🇸

Fresno, California, United States

Kaiser Permanente-Fresno

🇺🇸

Fresno, California, United States

Marin Cancer Care Inc

🇺🇸

Greenbrae, California, United States

Loma Linda University Medical Center

🇺🇸

Loma Linda, California, United States

Kaiser Permanente-Irvine

🇺🇸

Irvine, California, United States

Memorial Medical Center

🇺🇸

Springfield, Illinois, United States

Palo Alto Medical Foundation-Camino Division

🇺🇸

Mountain View, California, United States

Kaiser Permanente-Modesto

🇺🇸

Modesto, California, United States

Palo Alto Medical Foundation-Gynecologic Oncology

🇺🇸

Mountain View, California, United States

Sutter Cancer Research Consortium

🇺🇸

Novato, California, United States

Alta Bates Summit Medical Center - Summit Campus

🇺🇸

Oakland, California, United States

Kaiser Permanente-Oakland

🇺🇸

Oakland, California, United States

Kaiser Permanente Oakland-Broadway

🇺🇸

Oakland, California, United States

Bay Area Tumor Institute

🇺🇸

Oakland, California, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center

🇺🇸

Orange, California, United States

Kaiser Permanente-Ontario

🇺🇸

Ontario, California, United States

Kaiser Permanente - Panorama City

🇺🇸

Panorama City, California, United States

Palo Alto Medical Foundation Health Care

🇺🇸

Palo Alto, California, United States

Kaiser Permanente-Rancho Cordova Cancer Center

🇺🇸

Rancho Cordova, California, United States

Eisenhower Medical Center

🇺🇸

Rancho Mirage, California, United States

Kaiser Permanente-Richmond

🇺🇸

Richmond, California, United States

Kaiser Permanente-Redwood City

🇺🇸

Redwood City, California, United States

Mercy Cancer Center - Rocklin

🇺🇸

Rocklin, California, United States

Rohnert Park Cancer Center

🇺🇸

Rohnert Park, California, United States

Kaiser Permanente-Roseville

🇺🇸

Roseville, California, United States

Sutter Roseville Medical Center

🇺🇸

Roseville, California, United States

Kaiser Permanente-Riverside

🇺🇸

Riverside, California, United States

The Permanente Medical Group-Roseville Radiation Oncology

🇺🇸

Roseville, California, United States

Sutter Cancer Centers Radiation Oncology Services-Roseville

🇺🇸

Roseville, California, United States

South Sacramento Cancer Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente-San Diego Zion

🇺🇸

San Diego, California, United States

Kaiser Permanente-Santa Teresa-San Jose

🇺🇸

San Jose, California, United States

Pacific Central Coast Health Center-San Luis Obispo

🇺🇸

San Luis Obispo, California, United States

Kaiser Permanente-San Marcos

🇺🇸

San Marcos, California, United States

Kaiser Permanente-San Rafael

🇺🇸

San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara

🇺🇸

Santa Clara, California, United States

Palo Alto Medical Foundation-Santa Cruz

🇺🇸

Santa Cruz, California, United States

Mission Hope Medical Oncology - Santa Maria

🇺🇸

Santa Maria, California, United States

Kaiser Permanente Cancer Treatment Center

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-Santa Rosa

🇺🇸

Santa Rosa, California, United States

Kaiser Permanente-South San Francisco

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-Stockton

🇺🇸

Stockton, California, United States

Sutter Pacific Medical Foundation

🇺🇸

Santa Rosa, California, United States

Palo Alto Medical Foundation-Sunnyvale

🇺🇸

Sunnyvale, California, United States

Sutter Cancer Centers Radiation Oncology Services-Vacaville

🇺🇸

Vacaville, California, United States

Kaiser Permanente-Vallejo

🇺🇸

Vallejo, California, United States

Northbay Cancer Center

🇺🇸

Vacaville, California, United States

Kaiser Permanente Medical Center-Vacaville

🇺🇸

Vacaville, California, United States

Kaiser Permanente-Woodland Hills

🇺🇸

Woodland Hills, California, United States

Epic Care Cyberknife Center

🇺🇸

Walnut Creek, California, United States

John Muir Medical Center-Walnut Creek

🇺🇸

Walnut Creek, California, United States

Kaiser Permanente-Walnut Creek

🇺🇸

Walnut Creek, California, United States

Woodland Memorial Hospital

🇺🇸

Woodland, California, United States

Boulder Community Hospital

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers - Centennial

🇺🇸

Centennial, Colorado, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

Saint Francis Cancer Center

🇺🇸

Greenville, South Carolina, United States

Rocky Mountain Cancer Centers-Penrose

🇺🇸

Colorado Springs, Colorado, United States

Southwest Oncology PC

🇺🇸

Durango, Colorado, United States

Mercy Medical Center

🇺🇸

Durango, Colorado, United States

Mountain Blue Cancer Care Center

🇺🇸

Golden, Colorado, United States

The Melanoma and Skin Cancer Institute

🇺🇸

Englewood, Colorado, United States

Poudre Valley Hospital

🇺🇸

Fort Collins, Colorado, United States

Rocky Mountain Cancer Centers - Swedish

🇺🇸

Englewood, Colorado, United States

Saint Mary's Hospital and Regional Medical Center

🇺🇸

Grand Junction, Colorado, United States

Good Samaritan Medical Center

🇺🇸

Lafayette, Colorado, United States

North Colorado Medical Center

🇺🇸

Greeley, Colorado, United States

Kaiser Permanente-Rock Creek

🇺🇸

Lafayette, Colorado, United States

Rocky Mountain Cancer Centers-Littleton

🇺🇸

Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood

🇺🇸

Lakewood, Colorado, United States

Kaiser Permanente-Lone Tree

🇺🇸

Lone Tree, Colorado, United States

Littleton Adventist Hospital

🇺🇸

Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Longmont

🇺🇸

Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge

🇺🇸

Lone Tree, Colorado, United States

Sky Ridge Medical Center

🇺🇸

Lone Tree, Colorado, United States

Longmont United Hospital

🇺🇸

Longmont, Colorado, United States

Saint Mary Corwin Medical Center

🇺🇸

Pueblo, Colorado, United States

Rocky Mountain Cancer Centers-Parker

🇺🇸

Parker, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo

🇺🇸

Pueblo, Colorado, United States

National Jewish Health-Northern Hematology Oncology

🇺🇸

Thornton, Colorado, United States

SCL Health Lutheran Medical Center

🇺🇸

Wheat Ridge, Colorado, United States

Rocky Mountain Cancer Centers-Thornton

🇺🇸

Thornton, Colorado, United States

Hartford Hospital

🇺🇸

Hartford, Connecticut, United States

The Hospital of Central Connecticut

🇺🇸

New Britain, Connecticut, United States

Norwalk Hospital

🇺🇸

Norwalk, Connecticut, United States

Beebe South Coastal Health Campus

🇺🇸

Frankford, Delaware, United States

Beebe Medical Center

🇺🇸

Lewes, Delaware, United States

Delaware Clinical and Laboratory Physicians PA

🇺🇸

Newark, Delaware, United States

Medical Oncology Hematology Consultants PA

🇺🇸

Newark, Delaware, United States

TidalHealth Nanticoke / Allen Cancer Center

🇺🇸

Seaford, Delaware, United States

Christiana Care Health System-Christiana Hospital

🇺🇸

Newark, Delaware, United States

Christiana Care Health System-Wilmington Hospital

🇺🇸

Wilmington, Delaware, United States

Kaiser Permanente-Capitol Hill Medical Center

🇺🇸

Washington, District of Columbia, United States

Beebe Health Campus

🇺🇸

Rehoboth Beach, Delaware, United States

Sibley Memorial Hospital

🇺🇸

Washington, District of Columbia, United States

Holy Cross Hospital

🇺🇸

Fort Lauderdale, Florida, United States

Mount Sinai Comprehensive Cancer Center at Aventura

🇺🇸

Aventura, Florida, United States

Sarasota Memorial Hospital

🇺🇸

Sarasota, Florida, United States

Sacred Heart Hospital

🇺🇸

Pensacola, Florida, United States

Mount Sinai Medical Center

🇺🇸

Miami Beach, Florida, United States

Emory University Hospital/Winship Cancer Institute

🇺🇸

Atlanta, Georgia, United States

Emory Saint Joseph's Hospital

🇺🇸

Atlanta, Georgia, United States

Augusta University Medical Center

🇺🇸

Augusta, Georgia, United States

Northeast Georgia Medical Center Braselton

🇺🇸

Braselton, Georgia, United States

Northside Hospital-Forsyth

🇺🇸

Cumming, Georgia, United States

Dekalb Medical Center

🇺🇸

Decatur, Georgia, United States

Northeast Georgia Medical Center-Gainesville

🇺🇸

Gainesville, Georgia, United States

Low Country Cancer Care

🇺🇸

Savannah, Georgia, United States

CTCA at Southeastern Regional Medical Center

🇺🇸

Newnan, Georgia, United States

Memorial Health University Medical Center

🇺🇸

Savannah, Georgia, United States

Pali Momi Medical Center

🇺🇸

'Aiea, Hawaii, United States

Summit Cancer Care-Memorial

🇺🇸

Savannah, Georgia, United States

Summit Cancer Care-Candler

🇺🇸

Savannah, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

🇺🇸

Savannah, Georgia, United States

Hawaii Cancer Care - Westridge

🇺🇸

'Aiea, Hawaii, United States

Queen's Cancer Center - Pearlridge

🇺🇸

'Aiea, Hawaii, United States

The Cancer Center of Hawaii-Pali Momi

🇺🇸

'Aiea, Hawaii, United States

Saint Luke's Cancer Institute - Boise

🇺🇸

Boise, Idaho, United States

Saint Alphonsus Cancer Care Center-Caldwell

🇺🇸

Caldwell, Idaho, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

Wilcox Memorial Hospital and Kauai Medical Clinic

🇺🇸

Lihue, Hawaii, United States

Kootenai Health - Coeur d'Alene

🇺🇸

Coeur d'Alene, Idaho, United States

Walter Knox Memorial Hospital

🇺🇸

Emmett, Idaho, United States

Idaho Urologic Institute-Meridian

🇺🇸

Meridian, Idaho, United States

Saint Luke's Cancer Institute - Fruitland

🇺🇸

Fruitland, Idaho, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Kootenai Cancer Clinic

🇺🇸

Sandpoint, Idaho, United States

Kootenai Clinic Cancer Services - Post Falls

🇺🇸

Post Falls, Idaho, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

Illinois CancerCare-Dixon

🇺🇸

Dixon, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

Northwestern Medicine Cancer Center Delnor

🇺🇸

Geneva, Illinois, United States

Western Illinois Cancer Treatment Center

🇺🇸

Galesburg, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

NorthShore University HealthSystem-Glenbrook Hospital

🇺🇸

Glenview, Illinois, United States

Sudarshan K Sharma MD Limited-Gynecologic Oncology

🇺🇸

Hinsdale, Illinois, United States

Northwestern Medicine Lake Forest Hospital

🇺🇸

Lake Forest, Illinois, United States

Loyola University Medical Center

🇺🇸

Maywood, Illinois, United States

Cancer Care Center of O'Fallon

🇺🇸

O'Fallon, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Good Samaritan Regional Health Center

🇺🇸

Mount Vernon, Illinois, United States

Marjorie Weinberg Cancer Center at Loyola-Gottlieb

🇺🇸

Melrose Park, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Valley Radiation Oncology

🇺🇸

Peru, Illinois, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

Parkview Regional Medical Center

🇺🇸

Fort Wayne, Indiana, United States

Woodland Cancer Care Center

🇺🇸

Michigan City, Indiana, United States

Franciscan Health Mooresville

🇺🇸

Mooresville, Indiana, United States

Memorial Hospital of South Bend

🇺🇸

South Bend, Indiana, United States

Central Care Cancer Center - Garden City

🇺🇸

Garden City, Kansas, United States

University of Kansas Hospital-Westwood Cancer Center

🇺🇸

Westwood, Kansas, United States

University of Kansas Cancer Center

🇺🇸

Kansas City, Kansas, United States

University of Kansas Health System Saint Francis Campus

🇺🇸

Topeka, Kansas, United States

HaysMed University of Kansas Health System

🇺🇸

Hays, Kansas, United States

Women's Cancer Care-Covington

🇺🇸

Covington, Louisiana, United States

Bronson Battle Creek

🇺🇸

Battle Creek, Michigan, United States

UMass Memorial Medical Center - Memorial Division

🇺🇸

Worcester, Massachusetts, United States

Saint Joseph Mercy Chelsea

🇺🇸

Chelsea, Michigan, United States

Lahey Medical Center-Peabody

🇺🇸

Peabody, Massachusetts, United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton

🇺🇸

Brighton, Michigan, United States

Winchester Hospital

🇺🇸

Winchester, Massachusetts, United States

Saint Joseph Mercy Canton

🇺🇸

Canton, Michigan, United States

Henry Ford Cancer Institute-Downriver

🇺🇸

Brownstown, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston

🇺🇸

Clarkston, Michigan, United States

Henry Ford Medical Center-Fairlane

🇺🇸

Dearborn, Michigan, United States

Newland Medical Associates-Clarkston

🇺🇸

Clarkston, Michigan, United States

Henry Ford Macomb Hospital-Clinton Township

🇺🇸

Clinton Township, Michigan, United States

West Michigan Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Ascension Borgess Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Borgess Medical Center

🇺🇸

Kalamazoo, Michigan, United States

Bronson Methodist Hospital

🇺🇸

Kalamazoo, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital

🇺🇸

Livonia, Michigan, United States

Michigan Breast Specialists-Macomb Township

🇺🇸

Macomb, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Medical Campus

🇺🇸

Macomb, Michigan, United States

Hope Cancer Clinic

🇺🇸

Livonia, Michigan, United States

Trinity Health Muskegon Hospital

🇺🇸

Muskegon, Michigan, United States

Cancer and Hematology Centers of Western Michigan - Norton Shores

🇺🇸

Norton Shores, Michigan, United States

Henry Ford Medical Center-Columbus

🇺🇸

Novi, Michigan, United States

Hope Cancer Center

🇺🇸

Pontiac, Michigan, United States

21st Century Oncology-Pontiac

🇺🇸

Pontiac, Michigan, United States

Newland Medical Associates-Pontiac

🇺🇸

Pontiac, Michigan, United States

Huron Medical Center PC

🇺🇸

Port Huron, Michigan, United States

Lake Huron Medical Center

🇺🇸

Port Huron, Michigan, United States

Spectrum Health Reed City Hospital

🇺🇸

Reed City, Michigan, United States

Lakeland Medical Center Saint Joseph

🇺🇸

Saint Joseph, Michigan, United States

Marie Yeager Cancer Center

🇺🇸

Saint Joseph, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights

🇺🇸

Sterling Heights, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC

🇺🇸

Saginaw, Michigan, United States

Ascension Saint Mary's Hospital

🇺🇸

Saginaw, Michigan, United States

Henry Ford Macomb Health Center - Shelby Township

🇺🇸

Shelby, Michigan, United States

Munson Medical Center

🇺🇸

Traverse City, Michigan, United States

Ascension Saint Joseph Hospital

🇺🇸

Tawas City, Michigan, United States

Saint John Macomb-Oakland Hospital

🇺🇸

Warren, Michigan, United States

Advanced Breast Care Center PLLC

🇺🇸

Warren, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Professional Building

🇺🇸

Warren, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch

🇺🇸

West Branch, Michigan, United States

Macomb Hematology Oncology PC

🇺🇸

Warren, Michigan, United States

Henry Ford West Bloomfield Hospital

🇺🇸

West Bloomfield, Michigan, United States

University of Michigan Health - West

🇺🇸

Wyoming, Michigan, United States

Huron Gastroenterology PC

🇺🇸

Ypsilanti, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

🇺🇸

Ypsilanti, Michigan, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Minnesota Oncology - Burnsville

🇺🇸

Burnsville, Minnesota, United States

Fairview Ridges Hospital

🇺🇸

Burnsville, Minnesota, United States

Cambridge Medical Center

🇺🇸

Cambridge, Minnesota, United States

Mercy Hospital

🇺🇸

Coon Rapids, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove

🇺🇸

Maple Grove, Minnesota, United States

Fairview Southdale Hospital

🇺🇸

Edina, Minnesota, United States

Unity Hospital

🇺🇸

Fridley, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood

🇺🇸

Maplewood, Minnesota, United States

Monticello Cancer Center

🇺🇸

Monticello, Minnesota, United States

New Ulm Medical Center

🇺🇸

New Ulm, Minnesota, United States

Fairview Northland Medical Center

🇺🇸

Princeton, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park

🇺🇸

Saint Louis Park, Minnesota, United States

North Memorial Medical Health Center

🇺🇸

Robbinsdale, Minnesota, United States

Regions Hospital

🇺🇸

Saint Paul, Minnesota, United States

United Hospital

🇺🇸

Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center

🇺🇸

Shakopee, Minnesota, United States

Ridgeview Medical Center

🇺🇸

Waconia, Minnesota, United States

Rice Memorial Hospital

🇺🇸

Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury

🇺🇸

Woodbury, Minnesota, United States

Central Care Cancer Center - Bolivar

🇺🇸

Bolivar, Missouri, United States

Cox Cancer Center Branson

🇺🇸

Branson, Missouri, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

Freeman Health System

🇺🇸

Joplin, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology

🇺🇸

Rolla, Missouri, United States

Mercy Hospital South

🇺🇸

Saint Louis, Missouri, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Saint Louis

🇺🇸

Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital

🇺🇸

Sainte Genevieve, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Missouri Baptist Outpatient Center-Sunset Hills

🇺🇸

Sunset Hills, Missouri, United States

Missouri Baptist Sullivan Hospital

🇺🇸

Sullivan, Missouri, United States

Community Hospital of Anaconda

🇺🇸

Anaconda, Montana, United States

Billings Clinic Cancer Center

🇺🇸

Billings, Montana, United States

Mercy Hospital Washington

🇺🇸

Washington, Missouri, United States

Great Falls Clinic

🇺🇸

Great Falls, Montana, United States

Saint James Community Hospital and Cancer Treatment Center

🇺🇸

Butte, Montana, United States

Saint Peter's Community Hospital

🇺🇸

Helena, Montana, United States

Kalispell Regional Medical Center

🇺🇸

Kalispell, Montana, United States

CHI Health Saint Francis

🇺🇸

Grand Island, Nebraska, United States

Heartland Hematology and Oncology

🇺🇸

Kearney, Nebraska, United States

GenesisCare USA - Henderson

🇺🇸

Henderson, Nevada, United States

Hope Cancer Care of Nevada

🇺🇸

Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Central

🇺🇸

Las Vegas, Nevada, United States

Sunrise Hospital and Medical Center

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Southwest

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Vegas Tenaya

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin

🇺🇸

Las Vegas, Nevada, United States

Radiation Oncology Associates

🇺🇸

Reno, Nevada, United States

Hackensack University Medical Center

🇺🇸

Hackensack, New Jersey, United States

AtlantiCare Surgery Center

🇺🇸

Egg Harbor Township, New Jersey, United States

Memorial Sloan Kettering Basking Ridge

🇺🇸

Basking Ridge, New Jersey, United States

The Cancer Institute of New Jersey Hamilton

🇺🇸

Hamilton, New Jersey, United States

Monmouth Medical Center

🇺🇸

Long Branch, New Jersey, United States

Monmouth Medical Center Southern Campus

🇺🇸

Lakewood, New Jersey, United States

Valley Health System-Hematology/Oncology

🇺🇸

Westwood, New Jersey, United States

Neurosurgeons of New Jersey-Ridgewood

🇺🇸

Ridgewood, New Jersey, United States

Robert Wood Johnson University Hospital Somerset

🇺🇸

Somerville, New Jersey, United States

Women's Cancer Care Associates LLC

🇺🇸

Albany, New York, United States

Northwell Health/Center for Advanced Medicine

🇺🇸

Lake Success, New York, United States

Memorial Sloan Kettering Commack

🇺🇸

Commack, New York, United States

Dickstein Cancer Treatment Center

🇺🇸

White Plains, New York, United States

State University of New York Upstate Medical University

🇺🇸

Syracuse, New York, United States

Randolph Hospital

🇺🇸

Asheboro, North Carolina, United States

Hope Women's Cancer Centers-Asheville

🇺🇸

Asheville, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro

🇺🇸

Goldsboro, North Carolina, United States

Novant Health Presbyterian Medical Center

🇺🇸

Charlotte, North Carolina, United States

Southeastern Medical Oncology Center-Clinton

🇺🇸

Clinton, North Carolina, United States

Onslow Memorial Hospital

🇺🇸

Jacksonville, North Carolina, United States

Novant Health Cancer Institute - Mount Airy

🇺🇸

Mount Airy, North Carolina, United States

Novant Health Cancer Institute - Statesville

🇺🇸

Statesville, North Carolina, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Sanford South University Medical Center

🇺🇸

Fargo, North Dakota, United States

Saint Elizabeth Boardman Hospital

🇺🇸

Boardman, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital

🇺🇸

Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center

🇺🇸

Columbus, Ohio, United States

Delaware Radiation Oncology

🇺🇸

Delaware, Ohio, United States

Orion Cancer Care

🇺🇸

Findlay, Ohio, United States

Miami Valley Hospital

🇺🇸

Dayton, Ohio, United States

Blanchard Valley Hospital

🇺🇸

Findlay, Ohio, United States

Mercy Cancer Center-Elyria

🇺🇸

Elyria, Ohio, United States

Miami Valley Hospital North

🇺🇸

Dayton, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

Armes Family Cancer Center

🇺🇸

Findlay, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Greater Dayton Cancer Center

🇺🇸

Kettering, Ohio, United States

Hillcrest Hospital Cancer Center

🇺🇸

Mayfield Heights, Ohio, United States

Mercy Health Perrysburg Cancer Center

🇺🇸

Perrysburg, Ohio, United States

First Dayton Cancer Care

🇺🇸

Kettering, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center

🇺🇸

Sandusky, Ohio, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

Dayton Physicians LLC - Troy

🇺🇸

Troy, Ohio, United States

Mercy Health - Saint Anne Hospital

🇺🇸

Toledo, Ohio, United States

University of Cincinnati Cancer Center-West Chester

🇺🇸

West Chester, Ohio, United States

UH Seidman Cancer Center at Saint John Medical Center

🇺🇸

Westlake, Ohio, United States

Oklahoma Cancer Specialists and Research Institute-Tulsa

🇺🇸

Tulsa, Oklahoma, United States

Saint Charles Health System

🇺🇸

Bend, Oregon, United States

Jefferson Abington Hospital

🇺🇸

Abington, Pennsylvania, United States

Saint Luke's University Hospital-Bethlehem Campus

🇺🇸

Bethlehem, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg

🇺🇸

Bethlehem, Pennsylvania, United States

Christiana Care Health System-Concord Health Center

🇺🇸

Chadds Ford, Pennsylvania, United States

Geisinger Medical Center

🇺🇸

Danville, Pennsylvania, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

Pocono Medical Center

🇺🇸

East Stroudsburg, Pennsylvania, United States

UPMC Pinnacle Cancer Center/Community Osteopathic Campus

🇺🇸

Harrisburg, Pennsylvania, United States

Cherry Tree Cancer Center

🇺🇸

Hanover, Pennsylvania, United States

Lewistown Hospital

🇺🇸

Lewistown, Pennsylvania, United States

Community Medical Center

🇺🇸

Scranton, Pennsylvania, United States

Geisinger Medical Oncology-Selinsgrove

🇺🇸

Selinsgrove, Pennsylvania, United States

Geisinger Cancer Services-Pottsville

🇺🇸

Pottsville, Pennsylvania, United States

Thomas Jefferson University Hospital

🇺🇸

Philadelphia, Pennsylvania, United States

Asplundh Cancer Pavilion

🇺🇸

Willow Grove, Pennsylvania, United States

Lankenau Medical Center

🇺🇸

Wynnewood, Pennsylvania, United States

AnMed Health Cancer Center

🇺🇸

Anderson, South Carolina, United States

Bristol Regional Medical Center

🇺🇸

Bristol, Tennessee, United States

Parkland Memorial Hospital

🇺🇸

Dallas, Texas, United States

Saint Joseph Regional Cancer Center

🇺🇸

Bryan, Texas, United States

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

🇺🇸

Houston, Texas, United States

Thompson Oncology Group-Oak Ridge

🇺🇸

Oak Ridge, Tennessee, United States

UT Southwestern/Simmons Cancer Center-Fort Worth

🇺🇸

Fort Worth, Texas, United States

Kaiser Permanente-Burke Medical Center

🇺🇸

Burke, Virginia, United States

Swedish Cancer Institute-Edmonds

🇺🇸

Edmonds, Washington, United States

Overlake Medical Center

🇺🇸

Bellevue, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton

🇺🇸

Bremerton, Washington, United States

PeaceHealth Saint Joseph Medical Center

🇺🇸

Bellingham, Washington, United States

PeaceHealth Saint John Medical Center

🇺🇸

Longview, Washington, United States

Swedish Cancer Institute-Issaquah

🇺🇸

Issaquah, Washington, United States

Jefferson Healthcare

🇺🇸

Port Townsend, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Gig Harbor

🇺🇸

Gig Harbor, Washington, United States

Providence Regional Cancer System-Lacey

🇺🇸

Lacey, Washington, United States

Virginia Mason Lynnwood Medical Center

🇺🇸

Lynnwood, Washington, United States

Virginia Mason Medical Center

🇺🇸

Seattle, Washington, United States

Pacific Gynecology Specialists

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Ballard Campus

🇺🇸

Seattle, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Jackson Hall

🇺🇸

Tacoma, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - North

🇺🇸

Spokane, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Valley

🇺🇸

Spokane Valley, Washington, United States

Swedish Medical Center-First Hill

🇺🇸

Seattle, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Downtown

🇺🇸

Spokane, Washington, United States

Providence Regional Cancer System-Shelton

🇺🇸

Shelton, Washington, United States

University of Washington Medical Center - Montlake

🇺🇸

Seattle, Washington, United States

Franciscan Research Center-Northwest Medical Plaza

🇺🇸

Tacoma, Washington, United States

MultiCare Tacoma General Hospital

🇺🇸

Tacoma, Washington, United States

PeaceHealth Southwest Medical Center

🇺🇸

Vancouver, Washington, United States

Northwest Medical Specialties PLLC

🇺🇸

Tacoma, Washington, United States

Tacoma/Valley Radiation Oncology Centers-Saint Joe's

🇺🇸

Tacoma, Washington, United States

Providence Saint Mary Regional Cancer Center

🇺🇸

Walla Walla, Washington, United States

Legacy Salmon Creek Hospital

🇺🇸

Vancouver, Washington, United States

West Virginia University Charleston Division

🇺🇸

Charleston, West Virginia, United States

United Hospital Center

🇺🇸

Bridgeport, West Virginia, United States

Providence Regional Cancer System-Yelm

🇺🇸

Yelm, Washington, United States

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

🇺🇸

Yakima, Washington, United States

WVUH-Berkely Medical Center

🇺🇸

Martinsburg, West Virginia, United States

West Virginia University Healthcare

🇺🇸

Morgantown, West Virginia, United States

Monongalia Hospital

🇺🇸

Morgantown, West Virginia, United States

Camden Clark Medical Center

🇺🇸

Parkersburg, West Virginia, United States

Aurora Cancer Care-Southern Lakes VLCC

🇺🇸

Burlington, Wisconsin, United States

Marshfield Clinic-Chippewa Center

🇺🇸

Chippewa Falls, Wisconsin, United States

Marshfield Medical Center-EC Cancer Center

🇺🇸

Eau Claire, Wisconsin, United States

Aurora Health Center-Fond du Lac

🇺🇸

Fond Du Lac, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay

🇺🇸

Green Bay, Wisconsin, United States

Aurora Health Care Germantown Health Center

🇺🇸

Germantown, Wisconsin, United States

Aurora Cancer Care-Grafton

🇺🇸

Grafton, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's

🇺🇸

Green Bay, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette

🇺🇸

Marinette, Wisconsin, United States

Mercyhealth Hospital and Cancer Center - Janesville

🇺🇸

Janesville, Wisconsin, United States

Aurora BayCare Medical Center

🇺🇸

Green Bay, Wisconsin, United States

Aurora Cancer Care-Kenosha South

🇺🇸

Kenosha, Wisconsin, United States

Marshfield Medical Center-Marshfield

🇺🇸

Marshfield, Wisconsin, United States

Aurora Cancer Care-Milwaukee

🇺🇸

Milwaukee, Wisconsin, United States

Marshfield Clinic-Minocqua Center

🇺🇸

Minocqua, Wisconsin, United States

Cancer Center of Western Wisconsin

🇺🇸

New Richmond, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Oconto Falls

🇺🇸

Oconto Falls, Wisconsin, United States

Marshfield Medical Center-Rice Lake

🇺🇸

Rice Lake, Wisconsin, United States

Aurora Cancer Care-Racine

🇺🇸

Racine, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan

🇺🇸

Sheboygan, Wisconsin, United States

Marshfield Medical Center-River Region at Stevens Point

🇺🇸

Stevens Point, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Sturgeon Bay

🇺🇸

Sturgeon Bay, Wisconsin, United States

Aurora Medical Center in Summit

🇺🇸

Summit, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers

🇺🇸

Two Rivers, Wisconsin, United States

Marshfield Clinic-Wausau Center

🇺🇸

Wausau, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center

🇺🇸

Wisconsin Rapids, Wisconsin, United States

Aurora West Allis Medical Center

🇺🇸

West Allis, Wisconsin, United States

Aurora Cancer Care-Milwaukee West

🇺🇸

Wauwatosa, Wisconsin, United States

Advance Oncology Center

🇵🇷

Aguadilla, Puerto Rico

Jewish Hospital

🇺🇸

Louisville, Kentucky, United States

Norton Hospital Pavilion and Medical Campus

🇺🇸

Louisville, Kentucky, United States

Baptist Health Louisville

🇺🇸

Louisville, Kentucky, United States

Norton Suburban Hospital and Medical Campus

🇺🇸

Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Norton Brownsboro Hospital and Medical Campus

🇺🇸

Louisville, Kentucky, United States

Michigan Breast Specialists-Warren

🇺🇸

Warren, Michigan, United States

Thompson Cancer Survival Center - West

🇺🇸

Knoxville, Tennessee, United States

Doctors Cancer Center

🇵🇷

Manati, Puerto Rico

Truman Medical Centers

🇺🇸

Kansas City, Missouri, United States

UNC Lineberger Comprehensive Cancer Center

🇺🇸

Chapel Hill, North Carolina, United States

Medical University of South Carolina

🇺🇸

Charleston, South Carolina, United States

Hawaii Cancer Care Inc - Waterfront Plaza

🇺🇸

Honolulu, Hawaii, United States

Kuakini Medical Center

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini

🇺🇸

Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha

🇺🇸

Honolulu, Hawaii, United States

Kaiser Permanente Moanalua Medical Center

🇺🇸

Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children

🇺🇸

Honolulu, Hawaii, United States

Tulane University Health Sciences Center

🇺🇸

New Orleans, Louisiana, United States

Virginia Commonwealth University/Massey Cancer Center

🇺🇸

Richmond, Virginia, United States

Montefiore Medical Center-Einstein Campus

🇺🇸

Bronx, New York, United States

Montefiore Medical Center-Weiler Hospital

🇺🇸

Bronx, New York, United States

Montefiore Medical Center - Moses Campus

🇺🇸

Bronx, New York, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

Mission Cancer and Blood - Laurel

🇺🇸

Des Moines, Iowa, United States

Baptist Health Lexington

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

University of Wisconsin Carbone Cancer Center

🇺🇸

Madison, Wisconsin, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

Southwest Gynecologic Oncology Associates Inc

🇺🇸

Albuquerque, New Mexico, United States

Saint Vincent Healthcare

🇺🇸

Billings, Montana, United States

Saint John's Hospital - Healtheast

🇺🇸

Maplewood, Minnesota, United States

University Hospitals Sharon Health Center

🇺🇸

Wadsworth, Ohio, United States

Saint Alphonsus Medical Center-Baker City

🇺🇸

Baker City, Oregon, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

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