Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A

Not Applicable

Completed

• Conditions: Hemophilia A; Prophylaxis

• Registration Number: NCT02362581
• Lead Sponsor: Chulalongkorn University

Brief Summary

Comparison of prophylaxis and on-demand treatment in children with moderate to severe hemophilia A.

This study determines to compare the efficacy of prophylaxis and on-demand treatment in moderate to severe hemophilia A children in King Chulalongkorn Memorial Hospital, Bangkok, Thailand

Detailed Description

Not available

Study Timeline

• Study Start: 2012-12
• Primary Completion: 2014-01
• Study Completion: 2014-01
• Study First Submitted: 2015-01-29
• Status Verified: 2015-02
• Study First Submitted QC: 2015-02-09
• Last Update Submitted: 2015-02-09
• Study First Posted: 2015-02-13
• Last Update Posted: 2015-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Age between 6 months to 18 years
• Diagnosis severe and moderate hemophilia A

Exclusion Criteria

• platelet < 100,000/mm3
• No factor VIII inhibitor

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Number of admission days	one year
Number of bleeding episodes require treatment	one year
number of school days lost	one year

Secondary Outcome Measures

Name	Time	Method
Quality of life score	one year
Amount of Facter VIII concentration used	one year
Joint scores	one year

Trial Locations

Locations (1)

pediatric Hemato-oncology department, King Chulalongkorn Memorial Hospital; 🇹🇭 Pratumwan, Bangkok, Thailand

pediatric Hemato-oncology department, King Chulalongkorn Memorial Hospital

🇹🇭Pratumwan, Bangkok, Thailand