Ocular Penetration of 1.5% Levofloxacin and 0.5% Moxifloxacin During Corneal Transplant Surgery

Phase 4

Terminated

• Conditions: Corneal Transplantation
• Interventions: Drug: 1.5% levofloxacin ophthalmic solution; Drug: 0.5% moxifloxacin ophthalmic solution

• Registration Number: NCT00764582
• Lead Sponsor: Santen Inc.

Brief Summary

Compare the corneal penetration of levofloxacin 1.5% and moxifloxacin 0.5% in patients undergoing penetrating keratoplasty (PK)

Detailed Description

Not available

Study Timeline

• Study Start: 2008-09
• Study First Submitted: 2008-09-26
• Study First Submitted QC: 2008-10-01
• Study First Posted: 2008-10-02
• Primary Completion: 2009-03
• Status Verified: 2009-08
• Last Update Submitted: 2009-08-24
• Last Update Posted: 2009-08-26

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	1.5% levofloxacin ophthalmic solution	-
2	0.5% moxifloxacin ophthalmic solution	-

Primary Outcome Measures

Name	Time	Method
Concentration of levofloxacin and moxifloxacin in the corneal tissue	Time of surgery

Secondary Outcome Measures

Name	Time	Method
Adverse Events	4 days