Use of Karanjadi Rasakriya Anjana in Klinnavartma (Ulcerative Blepharitis)

Phase 2/3

Not yet recruiting

• Conditions: Blepharitis. Ayurveda Condition: VARTMA-ROGAH,

• Registration Number: CTRI/2025/04/085910
• Lead Sponsor: Dr Ajay Omprakash Kadam

Brief Summary

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|According to Ayurved Urdhvanga means ShalakyaTantra which is one of the most important and finest branch of Ashtang Ayurved. In Sushrut Samhita, Acharya SushrutExplained Netra Rachana, Netragat Vyadhiand its Chikitsa in Uttartantra.

Klinnavartma is one among the 76 Netraroga’s explained by Aacharya  Sushrut Klinnavartma is a Vartmagat Netrarog mentioned by Aacharya Sushrut as sadhya vyadhi .

In Ayurveda, Klinnavartma refers to a specific eye disease characterized by excessive watering and discharge from the eyes. This condition is often linked to an imbalance in the doshas, particularly an excess of Kapha. Symptom of Klinnavartma can includes state of excessive moisture ,Itching ,pricking pain, discharge.

In modern science, Klinnavartma can be correlated with Ulcerative blepharitis, a common inflammatory condition of the eyelids. Both conditions involve similar symptoms.The term Blepharitis consists of two words ’Blepharon’ (a Greek word) means eyelid and -itis means inflammation.

Bacterial blepharitis, also known as chronic anterior blepharitis, or staphylococcal blepharitis or ulcerative blepharitis, is a chronic infection of the anterior part of the lid margin.

In the Sushrut Samhita, Dalhan explains that "Klinnavartma," also referred to as "Pilla" . Acharya vaghbhat describe the treatment of pilla roga, in this he used Karanjadi Rasakriya Anjana.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-05
• Last Update Posted: 2025-04-04

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 84

Inclusion Criteria

• Shows symptoms of Klinnavartma.
• Patient with age aboven 18 yrs to 60 years will be included.
• Patient irrespective of Gender, educational, socioeconomic, marital status.

Exclusion Criteria

• Any other active acute infective ocular diseases.
• Patient have allergic to Drugs.
• Recently operated eye below 1 month.
• Patient having systemic Disease likes DM.
• Congenital anomalies of eye.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Karanjadi Rasakriya Anjana is effective in management of Klinnavartma	7 Days

Secondary Outcome Measures

Name	Time	Method
Dhatryanjana is effective in mamagement of Klinnavartma	7 Days

Trial Locations

Locations (1)

Hon Shri Annasaheb Dange Ayurved Medical College And Research Center Ashta; 🇮🇳 Sangli, MAHARASHTRA, India

Hon Shri Annasaheb Dange Ayurved Medical College And Research Center Ashta

🇮🇳Sangli, MAHARASHTRA, India

Dr Ajay Omprakash Kadam

Principal investigator

7972860998

ajaykadam5896@gmail.com