Efficacy of Aliskiren in hypertensive patients with diabetes mellitus or obesity
Not Applicable
Recruiting
- Conditions
- Essential hypertensive patients with type II diabetes or obesity
- Registration Number
- JPRN-UMIN000011865
- Lead Sponsor
- Tokyo Women's Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 104
Inclusion Criteria
Not provided
Exclusion Criteria
1. type I diabetes mellitus 2. HbA1c>9.0% 3. CKD group IV or higher 4. hyperkalemia 5. unstable angina pectoris 6. occurrence of acute myocardial infarction or stroke within 24 weeks 7. severe liver dysfunction 8. pregnancy or lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method changes in visceral fat area and waist circumference
- Secondary Outcome Measures
Name Time Method changes in 1. BMI 2. HOMA-IR 3. FBS, HbA1c 4. Blood pressure, pulse rate, renal function 5. lipid profiles 6. components of renin-angiotensin system 7. urinary 8-OHdG 8. hsCRP, PTX3 9. endothelial function(FMD) 10. atherosclerosis(CAVI, AI, IMT)