PACTR201512001388104
Not yet recruiting
未知
Comparison between pressure regulated volume-controlled (PRVC) and volume-controlled (VC) ventilation on oxygenation parameters, airway pressures and immune-modulation during thoracic surgery.
Minoufiya University0 sites50 target enrollmentDecember 13, 2015
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Respiratory
- Sponsor
- Minoufiya University
- Enrollment
- 50
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •adult patients ASA I\-III undergoing elective open thoracic surgery using one lung ventilation.
Exclusion Criteria
- •Preoperative exclusion criteria will include patient refusal, significant lung diseases {forced expiratory volume in 1 s (FEV1\) or vital capacity (VC) \< 50% of the predicted values}, uncompensated cardiac disease or mean pulmonary artery pressure (MPAP) \> 30 mm Hg, hepatic or renal disease, coagulation disorders or a history of pre\-operative immuno\-suppressant medications. Intraoperative exclusion criteria will include inability to maintain an appropriate arterial oxygen saturation(SpO2\) and end\-tidal carbon dioxide (EtCO2\), inability to keep stable mechanical ventilation settings for 30 min, , abnormal surgical complications, and prolonged hemodynamic instability
Outcomes
Primary Outcomes
Not specified
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