Increasing the Yield of Blood Cultures in Neonates

Not Applicable

Completed

• Conditions: Bacteremia
• Interventions: Other: 1cc of blood in a single aerobic culture bottle

• Registration Number: NCT01023555
• Lead Sponsor: Shaare Zedek Medical Center

Brief Summary

The purpose of this study is to determine whether the use of a single blood sample of 1cc in an aerobic bottle will provide a better yield and time to positivity than 2 samples of 0.5 cc in 2 (aerobic and anaerobic) bottles for blood cultures in neonates.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-12-01
• Study First Submitted QC: 2009-12-01
• Study First Posted: 2009-12-02
• Study Start: 2010-01
• Primary Completion: 2010-07
• Study Completion: 2010-07
• Status Verified: 2011-07
• Last Update Submitted: 2011-07-24
• Last Update Posted: 2011-07-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• All blood cultures taken in the NICU during the study period.

Exclusion Criteria

• Bacteria that are normal flora of the skin such as Coagulase negative staphylococci or Streptococci Viridans are considered, except if grown in two sets of cultures or in the presence of laboratory and clinical indices of infection.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1cc single bottle	1cc of blood in a single aerobic culture bottle	-

Primary Outcome Measures

Name	Time	Method
Non Inferiority of 1 cc blood culture in a single aerobic bottle instead of 0.5 cc for 2 bottles.	6months

Secondary Outcome Measures

Name	Time	Method
utility of the routine use of anaerobic bottle for blood cultures in newborns	6 months
Comparison of time to positivity of 1 cc blood culture in a single aerobic bottle instead of 0.5 cc for 2 bottles (aerobic and anaerobic)	6 months