Measurement of upper extremity function in persons with neuromuscular diseases (NMD)

Conditions: muscular dystrophy
neuromuscular diseases
10029299
10028302

Registration Number: NL-OMON39775

Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 24

Inclusion Criteria

6 healthy control subjects
5-10 persons with confirmed diagnosis of spinal muscular atrophy
6 persons with confirmed diagnosis of fascioscapulohumeral dystrophy
6 persons with confirmed dignosis of limb girdle muscular dystrophy
All persons with a neuromuscular disease have impaired function of the upper extremity with a score on the Brooke scale of 3 or 4.
All persons are able to sit in a (wheel)chair with a low back rest

Exclusion Criteria

Other diseases impairing arm function
inability to come to the movement analysis laboratory
inability to cooperate

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Registration of single movements:<br /><br>Shoulder abduction (straight arm), shoulder anteflexion (straight arm)<br /><br>shoulder abduction (elbow flexed 90)<br /><br>shoulder anteflexion (elbow flexed 90) shoulder internal rotation, shoulder<br /><br>adduction in horizontal plane (Only with arm support)<br /><br><br /><br>Movement Registration of functional movements:<br /><br>Bringing the hand to the mouth (active flexion and supination of the arm and<br /><br>passive pronation)<br /><br>Reaching to the left and right (active protraction of the scapula)<br /><br>Pulling and pushing a light object on a table<br /><br><br /><br>EMG measures:<br /><br>m. biceps brachii<br /><br>- m. lateral deltoid<br /><br>- m. triceps brachii<br /><br>- m. trapezius descendens<br /><br>- m. pectoralis major<br /><br><br /><br>Maximum Voluntary Contraction<br /><br>- m. biceps brachii<br /><br>- m. lateral deltoid<br /><br>- m. triceps brachii<br /><br>- m. trapezius descendens<br /><br>- m. pectoralis major</p><br>

Secondary Outcome Measures