Evaluation and comparison of the usage of a novel prebiotic as an adjunct to Scaling and Root Planing in the treatment of periodontitis A randomized controlled clinical trial.

TITLE- Evaluation And Comparison Of The Usage Of A Novel Prebiotic As An Adjunct To Scaling And Root Planing (SRP) Versus SRP Alone In The Non-Surgical Treatment Of Chronic Periodontitis: A Pilot Study.

 INTRODUCTION- Host modulation using prebiotics like high-molecular-weight inulin enhances gut microbiota, reducing endotoxemia and systemic inflammation. It lowers periodontal inflammation and prevents periodontal tissue degradation by improving immune response.

OBJECTIVE – To evaluate and compare the effectiveness of a novel prebiotic as an adjunct to SRP versus SRP alone on clinical periodontal parameters in individuals undergoing nonsurgical periodontal therapy.

**PRIMARY HYPOTHESIS-**There is a difference between the effectiveness of a novel prebiotic as an adjunct to SRP versus SRP alone in the nonsurgical treatment of Chronic Periodontitis.

**NULL HYPOTHESIS-**There is no difference between the effectiveness of a novel prebiotic as an adjunct to SRP versus SRP alone in the nonsurgical treatment of Chronic Periodontitis.

METHODOLOGY- The test group received 10mg inulin powder (5mg in the morning and 5 mg in the evening) mixed with water for 2 weeks before SRP and continued for 2 months, while the control group underwent SRP alone. Clinical parameters, Plaque index (PI), Gingival Index (GI), Bleeding on Probing (BOP), Pocket probing depth (PPD), Clinical Attachment Loss (CAL), were assessed at baseline, 1 month and 2 months.