IRCT138711051556N1
Completed
Phase 2
Saffron extract in the treatment of mild to moderate Alzheimer’s disease: A double blind randomized controlled trial.
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Tehran University of Medical Sciences
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion Criteria:
- •A diagnosis of probable Alzheimer’s disease according to the criteria of National Institute of Neurological and Communicative Disorders and Stroke and Alzheimer’s Disease and Related Disorders Association (NINCDS/ADRDA); Presence of mild to moderate dementia \[score of \= 12 on the cognitive subscale of Alzheimer’s Disease Assessment Scale (ADAS\-cog) and \= 2 on Clinical Dementia Rating Scale (CDR)].
Exclusion Criteria
- •Concomitant diseases such as hypertension, congestive heart failure, non\-insulin dependent diabetes mellitus and hypothyroidism; Patients with evidence of other neurodegenerative disorders; Any cardiovascular disease likely to prevent completion of the study; Clinically significant psychiatric diseases; Urinary outflow obstruction; Active peptic ulcer; Any history of epilepsy; Significant drug or alcohol misuse; Drugs with anticholinergic effects or cholinomimetic effects.
Outcomes
Primary Outcomes
Not specified
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