Comparison of nalbuphine versus morphine for the recovery of bowel functio
Phase 4
- Conditions
- Patient undergoing elective laparoscopic colonic surgeryEnhanced recovery after colon and rectal surgery, ERAS, Nalbuphine, Recovery of bowel function
- Registration Number
- TCTR20211012002
- Lead Sponsor
- Ratchadaphiseksomphot endowment fund, Faculty of Medicine Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
1. Patient undergoing elective laparoscopic colonic surgery, 2. ASA physical status classification I-III
Exclusion Criteria
1. Allergy to research medications, 2. Inability to communicate pain, 3. Inability to use PCA, 4. Open surgery, 5. Ostomy, 6. Chronic pain more than 3 months or a history of chronic opioid use, 7. Postoperative ICU and remained intubate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method colonic transit time 5 days after surgery Number of radiopaque markers (Sitz marks) in plain film abdomen
- Secondary Outcome Measures
Name Time Method umerical pain score at rest at 24h 24 hour after surgery Numerical pain score,Numerical pain score on movement at 24h 24 hour after surgery Numerical pain score,PCA opioid consumption 24 hour after surgery milligrams and morphine equivalent doses,Incidence of post operative ileus within 5 days after surgery defined as 3 episodes of first 24 h after surgery (milligrams and vomiting over 24 hours, cessation of oral diet, or need for nasogastric tube within 5 days after surgery,time to first flatus after surgery hour