To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis
Phase 3
- Conditions
- Chorioretinitis
- Interventions
- Drug: Clindamycin+Dexamethasone
- Registration Number
- NCT00372294
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Toxoplasmosis, an intra cellular parasite, is a very important cause of chorioretinitis. The goal of treatment is arresting multiplication of the parasite in its inflammatory active phase. In this study the investigators try to compare the efficacy of the classic regimen (Pyrimethamine-Sulfadiazine + Prednisolon) with intravitreal Clindamycin \& Dexamethasone.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Patients with Toxoplasmic chorioretinitis
- Location of the lesion within zone I of the retina or a lesion greater than 2DD with 3+-4+ vitreous inflammation in zone II or III
- No allergic history to the used drugs
- No any other diseases
Exclusion Criteria
- Any allergic reaction to the used medications
- One eyed patients
- Partially treated patients
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 pyrimethamine-sulfadiazine + prednisolone Classic regimen (Pyrimethamine-Sulfadiazine + Prednisolon) 2 Clindamycin+Dexamethasone Intravitreal Clindamycin \& Dexamethasone
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ophthalmic Research Center
🇮🇷Tehran, Iran, Islamic Republic of
Ophthalmic Research Center🇮🇷Tehran, Iran, Islamic Republic of