NCT00372294Unknown3 期
To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 试验地点
- 1
研究概览
简要总结
Toxoplasmosis, an intra cellular parasite, is a very important cause of chorioretinitis. The goal of treatment is arresting multiplication of the parasite in its inflammatory active phase. In this study the investigators try to compare the efficacy of the classic regimen (Pyrimethamine-Sulfadiazine + Prednisolon) with intravitreal Clindamycin & Dexamethasone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Toxoplasmic chorioretinitis
- •Location of the lesion within zone I of the retina or a lesion greater than 2DD with 3+-4+ vitreous inflammation in zone II or III
- •No allergic history to the used drugs
- •No any other diseases
排除标准
- •Any allergic reaction to the used medications
- •One eyed patients
- •Partially treated patients
研究组 & 干预措施
1
Active Comparator
Classic regimen (Pyrimethamine-Sulfadiazine + Prednisolon)
干预措施: pyrimethamine-sulfadiazine + prednisolone (Drug)
2
Active Comparator
Intravitreal Clindamycin & Dexamethasone
干预措施: Clindamycin+Dexamethasone (Drug)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Intravitreal Dexamethason treatment of bacterial endophthalmitis.EndophthalmitisNL-OMON28649Het Oogziekenhuis Rotterdam150
Unknown
不适用
Intraocular injection of Clindamycin and Dexamethazone in the management of Toxoplasma infection of the retinaCTRI/2017/08/009443il
招募中
2 期
Dexamethasone for Cerebral ToxoplasmosisToxoplasmosis, CerebralNCT04341155Universitas Padjadjaran138
招募中
4 期
A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract SurgeryPatient PreferenceNCT04205916Ophthalmic Consultants of Long Island50
已完成
不适用
Intravitreal dexamethasone treatment of bacterial endophthalmitisPost-operative bacterial endophthalmitisEye DiseasesDisorders of globeISRCTN77234772Rotterdam Eye Hospital (Oogziekenhuis Rotterdam) (The Netherlands)150