A COMPARATIVE STUDY OF DEXMEDITOMIDINE VERSUS FENTANYL FOR ATTENUATION OF HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- TO STUDY THE COMPARISION OF DEXMEDITOMIDINE AND FENTANYL IN ATTENUATION OF HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION
研究概览
简要总结
THIS IS A PROSPECTIVE RANDAMISED DOUBLE BLINDED STUDY. IT HAS A SAMPLE SIZE OF 60 PATIENTS ADMITTED FOR ELECTIVE SURGERIES UNDER GA .
THE PRIMARY AIM OF THR STUDY IS TO COMPARE DEXMEDETOMISINE AND FENTANYL IN ATTENUATON OF HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION.
THE SECONDARY OBJECTIVE OF THE STUDY IS TO COMPARE THE LEVEL OF ANALGESIA AND SEDATION IN THE POST OPERATIVE PERIOD OFR 24 HRS .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •PATIENTS GIVING VALID INFORMED CONSENT ASA GRADE 1 AND 2 AGE BETWEEN 20 TO 60 YEARS OF AGE ELECTIVE SURGERIES UNDER GA.
排除标准
- •PATIENT REFUSAL ASA GRADE 3 AND 4 AGE LESS THAN 20 AND MORE THAN 60 PREGNANCY OBESITY FULL STOMACH AND EMERGENCY SURGERY PATIENTS SUFFERING FROM CARDIOVASCULAR DISEASES PATIENTS WITH METABOLIC DISORDERS PATIENS WITH DIFFICULT AIRWAY.
结局指标
主要结局
TO STUDY THE COMPARISION OF DEXMEDITOMIDINE AND FENTANYL IN ATTENUATION OF HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION
时间窗: Hemodynamic parameters (HR, SBP, DBP, MAP) will be measured at: | 1.Baseline (before study drug administration) | 2.After study drug administration – just before induction | 3.Before laryngoscopy and intubation (pre-intubation) | 4.During laryngoscopy | 5.Immediately after intubation (0 minute) | 6.1 minute after intubation | 7.3 minutes after intubation | 8.5 minutes after intubation | 9.10 minutes after intubation
次要结局
- TO EVALUATE THE LEVEL OF ANALGESIA AND SEDATION IN THE POST OPERATIVE PERIOD(UNTIL 24 HOURS POST SURGERY)
研究者
DR ARUN KUMAR B
Vinayaka missions Kirupanandha Variyar Medical College , Salem - 636308