Muscle Oxygenation and Spasticity in Hemiparetic Stroke Patients
- Conditions
- StrokeHemiparesis;Poststroke/CVASpasticity as Sequela of Stroke
- Interventions
- Other: Assessment
- Registration Number
- NCT06362954
- Lead Sponsor
- Ankara Medipol University
- Brief Summary
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment, cognitive impairment, aphasia, and dysphagia may be observed after stroke. Motor impairment after stroke may occur due to damage to any part of the brain related to motor control. There is much clinical evidence that damage to different parts of the sensorimotor cortex in humans affects other aspects of motor function. Loss of strength, spasticity, limb apraxia, loss of voluntary movements, Babinski sign, and motor neglect are typical motor deficits following a cortical lesion (upper motor neuron lesion). Post-stroke spasticity can be seen in 19% to 92% of stroke survivors. Post-stroke hemiparesis is a significant cause of morbidity and disability, along with abnormal muscle tone. It has also been recognized that post-stroke hemiparesis may occur without spasticity. Spasticity influences muscle hemodynamic and oxidative metabolism, but its impact on the balance between oxygen delivery and utilization is not well understood.
This study study aims to investigate the effect of spasticity severity on peripheral muscle oxygenation in patients with hemiparetic stroke.
- Detailed Description
Conditions such as hemiparesis, sensory and motor impairment, perceptual impairment, cognitive impairment, aphasia, and dysphagia may be observed after stroke. Motor impairment after stroke may occur due to damage to any part of the brain related to motor control. There is much clinical evidence that damage to different parts of the sensorimotor cortex in humans affects other aspects of motor function. Loss of strength, spasticity, limb apraxia, loss of voluntary movements, Babinski sign, and motor neglect are typical motor deficits following a cortical lesion (upper motor neuron lesion). Post-stroke spasticity can be seen in 19% to 92% of stroke survivors. Post-stroke hemiparesis is a significant cause of morbidity and disability, along with abnormal muscle tone. It has also been recognized that post-stroke hemiparesis may occur without spasticity. Spasticity influences muscle hemodynamic and oxidative metabolism, but its impact on the balance between oxygen delivery and utilization is not well understood.
Motor deficits seen in stroke patients and the conditions caused by them cause various limitations in the daily life of patients and affect their participation in daily life and quality of life. Decreased involvement in daily life negatively affects patients both socially and financially. Evaluating and identifying the disorders, taking preventive and developmental measures, and establishing treatment programs are necessary to increase participation. Therefore, objective and accurate assessment significantly affects the progress of the process.
Medical and surgical treatment and physiotherapy and rehabilitation approaches constitute the basis of treatment in stroke disease. The treatment of patients is carried out using a multidisciplinary approach involving many fields, such as medical and surgical treatment, physiotherapy, and rehabilitation practices. For this reason, it is seen that the financial burden, which cannot be covered by the insurance system from time to time, is relatively high. This burden is gradually increasing in direct proportion to the needs of the patients. For this reason, it is essential to develop practices and strategies for the patient's objective and most accurate evaluation, follow the clinical course, and create the most appropriate treatment program.
Although it is not among the routine evaluation methods, considering the studies conducted, "muscle oxygenation" should be considered in the evaluation phase in line with the possibilities.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description High-Level Spasticity Assessment Hemiparetic stroke patients with spasticity levels 3 and 4 on The Modified Ashworth Scale Low-Level Spasticity Assessment Hemiparetic stroke patients with spasticity levels between 1 and 2 on The Modified Ashworth Scale No Spasticity Assessment Hemiparetic stroke patients with spasticity level 0 on The Modified Ashworth Scale
- Primary Outcome Measures
Name Time Method Gastrocnemius Muscle Oxygenation Day 1 Gastrocnemius muscle oxygenation will be evaluated with Near-Infrared Spectroscopy at rest, during and after the 6-Minute Walk Test (6MWT) and the Stair Climbing Test (SCT).
Spasticity Day 1 Plantar flexor muscle spasticity on the affected side will be evaluated with Modified Ashworth Scale
- Secondary Outcome Measures
Name Time Method Motor Function Day 1 Motor function of the affected limb was assessed using the leg and foot sections of the Chedoke-McMaster Stroke Assessment (1-7 scale).
Disability Level Day 1 Disability level was determined using the Modified Rankin Scale, which ranges from 0 (no symptoms) to 6 (death).
6-Minute Walk Test Day 1 Submaximal functional capacity will be evaluated with 6-Minute Walk Test during muscle oxygenation measurement.
Stair Climbing Test Day 1 Maximal functional capacity will be evaluated with Stair Climbing Test during muscle oxygenation measurement.
Adipose tissue thickness Day 1 The skinfold thickness of gastrocnemius muscle was evaluated with a Skinfold Caliper. Adipose tissue thickness was obtained by dividing the skinfold thickness by two.
Trial Locations
- Locations (1)
Gazi University, Faculty of Health, Department of Physiotherapy and Rehabilitation
🇹🇷Ankara, Turkey