A Open labelled Randomised controlled trial to compare the efficacy of Carbetocin and Oxytocin in preventing post partum haemorrhage in uncomplicated elective caesarean sections at a tertiary care centre in Telangana

open-label randomized controlled trial aims to compare the efficacy of carbetocin versus oxytocin in preventing postpartum hemorrhage (PPH) following uncomplicated elective caesarean sections. The study will be conducted over 18 months at AIIMS Bibinagar, involving 200 pregnant women randomly assigned to receive either carbetocin or oxytocin during surgery. Intraoperative blood loss will be measured using mop weight and suction canister volume, while postpartum blood loss will be visually estimated over 24 hours. Secondary outcomes include the need for additional uterotonics, surgical interventions, blood transfusions, and adverse drug effects. Participants will be selected based on strict inclusion and exclusion criteria to ensure uniformity. Randomization will be done using permuted blocks and allocation concealed in sealed envelopes. Hemoglobin levels will be assessed pre- and post-operatively to evaluate blood loss impact. Data will be analyzed using Stata 18, applying appropriate statistical tests for continuous and categorical variables. The study seeks to generate evidence on which uterotonic agent offers superior efficacy and safety in PPH prevention. Results will inform clinical practice in obstetric care during cesarean deliveries.