A randomized controlled clinical study of Tonglin Guben Recipe on CIRF outcome after soft endoscopy for renal calculi

Phase 1

• Conditions: renal calculus

• Registration Number: ITMCTR2200006638
• Lead Sponsor: The Second Affiliated Hospital of Guangzhou University of traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

? Patients aged 18-70 years with renal calculi diagnosed by CT before operation;

? Patients with ureteroscopic lithotripsy and indwelling double J tube after operation;

? The intraoperative lithotripsy was successful (the maximum residual stone fragment measured at 4mm of the exposed part of holmium laser during the operation was = 4 mm, no obvious ureteral perforation, mucosal exfoliation, kidney bladder injury, severe bleeding and other intraoperative complications were found during the operation, which met the success criteria of the operation), and the postoperative kub and abdominal (double kidney) CT confirmed that the maximum residual stone diameter was = 4 mm.
? Those who are willing to participate in this study and can actively cooperate with follow-up visits and complete clinical observation.

Exclusion Criteria

? Patients with lower urinary tract obstruction;
? Patients with X - ray negative calculi were diagnosed before operation;
? Patients with ureteral perforation, mucosal exfoliation, kidney or bladder injury, severe bleeding and other complications during the operation;
? Pregnancy, lactation or 3 months of childbearing demand;
? Uremic patients, diabetes patients who have undergone renal transplantation and whose blood glucose can not be controlled, and patients with liver dysfunction (ALT or ast > twice the upper limit of normal);
? Patients with this disease were treated with lithotripsy drugs in the past week;
? Known hypersensitivity to test drug components;
? Patients with acute and chronic renal failure;
? Those who participate in other clinical researches within six months;
? The researcher thinks it is not suitable for the candidates.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effective rate of treatment;Stone elimination;Stone discharge and time;