Measurement of Pulse Pressure Variation and Cardiac Output by a New Application for Android™ (Captesia™)

Completed

• Conditions: Coronary Bypass
• Interventions: Other: Calculation of PPV and CO with two methods

• Registration Number: NCT02692222
• Lead Sponsor: Erasme University Hospital

Brief Summary

This study test the agreement and accuracy of Pulse Pressure Variation (PPV) and Cardiac Output (CO) obtained by the Android application Capstesia™ against the gold standard : PPV and CO calculated by thermodilution.

Detailed Description

Pulse pressure variation (PPV) remains a good predictor of fluid responsiveness in the OR. However, PPV can be time-consuming to calculate (manual determination), is not always displayed on monitoring screens nor reliable through visual assessment and needs additional devices to be displayed. A new Android application (Captesia) automatically calculates the PPV utilizing a digital photograph of the arterial waveform from the monitor. The application determines the PPV by selecting peaks and troughs of the arterial curve.

Study Timeline

• Study Start: 2016-02
• Study First Submitted: 2016-02-10
• Study First Submitted QC: 2016-02-22
• Study First Posted: 2016-02-26
• Status Verified: 2016-12
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Last Update Submitted: 2016-12-06
• Last Update Posted: 2016-12-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 57

Inclusion Criteria

• patients scheduled for coronary artery bypass

Exclusion Criteria

• patients with arrhythmias like atrial fibrillation
• patients with valvular insufficiency

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
PPV	Calculation of PPV and CO with two methods	This study will track changes in PPV and CO before and after of volume expansion, which goal is to change the cardiac output.

Primary Outcome Measures

Name	Time	Method
PPV	at time of surgery	the Pulse Pressure Variation will be calculated by the Android Application (Captesia) and by the Picco before and after a meneuver of volume expansion, which goal is to change the cardiac output.

Secondary Outcome Measures

Name	Time	Method
CO	at time of surgery	the Cardiac Output will be calculated by the Android Application (Captesia) and by thermodilution before and after of volume expansion, which goal is to change the cardiac output.

Trial Locations

Locations (1)

Erasme Hospital; 🇧🇪 Bruxelles, Belgium